ReviewInternational journal of molecular sciences2021
Association of Sleep Architecture and Physiology with Depressive Disorder and Antidepressants Treatment.
Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Efficacy and safety of a selective partial agonist for nociception/orphanin-FQ peptide (NOP) receptors in patients with insomnia disorder.British journal of clinical pharmacology · 2026Trial
- People with IBD evidence more microarousals during sleep architecture assessments.BMJ open gastroenterology · 2023Trial
- Sleep impairments in refugees diagnosed with post-traumatic stress disorder: a polysomnographic and self-report study.European journal of psychotraumatology · 2023Trial
- The Relationship of Early Sleep Improvement With Response to Pharmacotherapy in Unipolar Psychotic Depression.Journal of clinical psychopharmacologyTrial
- Electroconvulsive Therapy and the Longitudinal Modulation of Sleep Architecture.The journal of ECT · 2026Article
- Slow Wave Sleep and Emotion Regulation in Adolescents With Depressive Symptoms: An Experimental Pilot Study.Journal of sleep research · 2025Article
- Article
- Associations of physical activity, sedentary time, sleep quality, and resting EEG with mild depressive symptoms in college students: a cross-sectional study.BMC public health · 2025Article
- Obstructive sleep apnea, periodic limb movements, and REM sleep without atonia are common in Parkinson's disease and correlate with motor symptom burden.Journal of Parkinson's disease · 2025Article
- Wearables as Translational Physiomarkers and Clinical Endpoints in Insomnia Research: Can Sleep Research Advance Psychiatry?Journal of sleep research · 2025Review
- Sleep architecture and quality of life in comorbid OSA and depression: cross-sectional analysis of the Sydney sleep biobank.Sleep & breathing = Schlaf & Atmung · 2025Article
- Multimodal integration of homotopic connectivity and transcriptomic signatures in major depressive disorder with sleep disorder comorbidity.BMC psychiatry · 2025Article
- Association Between Sleep Quality and Cognitive Complaints Among Young Adults With Migraine.Cureus · 2025Article
- Risk of Major Depression Associated with Excessive Daytime Sleepiness in Apneic Individuals.Clocks & sleep · 2025Article
- Clinical predictors of insomnia in borderline personality disorder: a polysomnographic and subjective examination.Borderline personality disorder and emotion dysregulation · 2025Article
- Article
- Effective Dexmedetomidine Dose for Stage N2 Sleep Induction and Associated Factors in Depression-Related Insomnia: A Polysomnography-Based Analysis.Nature and science of sleep · 2025Article
- Mind-Body Interventions for Comorbid Sleep and Gastrointestinal Concerns.Current sleep medicine reports · 2025Review
- Optimizing the diagnosis and treatment of depression in primary care: the emerging role of vortioxetine treatment.Frontiers in psychiatry · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Sleep problems are frequently associated with the principal diagnostic criteria for many mental disorders. Alterations in the sleep of depressive patients are of high clinical significance because continuous sleep problems raise the chance of relapse, recurrence, or suicide, as well as the need for augmenting medications. Most antidepressants have been proven to influence the sleep architecture. While some classes of antidepressants improve sleep, others may cause sleep impairment. The successful treatment of depressive disorder also requires an understanding of the effects of antidepressants on sleep. This article briefly reviews the physiology of sleep and the typical alterations in the sleep architecture in depressive patients and updates the different effects of the majority of antidepressants including novel drugs in clinical practice on sleep. The summary of the updated scientific findings of the relationship between depression and sleep disturbances could be clinically beneficial in choosing the best medication for depressive patients with concurrent sleep disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.