Evidence map›Paper›PMID 33572733›Full record

ArticleMolecules (Basel, Switzerland)2021

Genomics-Driven Activation of Silent Biosynthetic Gene Clusters in

Hanna Chen, Tao Sun, Xianping Bai, Jie Yang, Fu Yan, Lei Yu, Qiang Tu, Aiying Li, Yajie Tang, Youming Zhang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. The Crucial Role of LTTR_0390 inJournal of agricultural and food chemistry · 2026
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  9. Recombineering in Non-Model Bacteria.Current protocols · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Hanna ChenHelmholtz International Lab for Anti-Infectives, Shandong University-Helmholtz Institute of Biotechnology, State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Tao SunHelmholtz International Lab for Anti-Infectives, Shandong University-Helmholtz Institute of Biotechnology, State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Xianping BaiHelmholtz International Lab for Anti-Infectives, Shandong University-Helmholtz Institute of Biotechnology, State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Jie YangHelmholtz International Lab for Anti-Infectives, Shandong University-Helmholtz Institute of Biotechnology, State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Fu YanHelmholtz International Lab for Anti-Infectives, Shandong University-Helmholtz Institute of Biotechnology, State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Lei YuSoil and Fertilizer Station of Shandong Province, Jinan 250100, China.
Qiang TuHelmholtz International Lab for Anti-Infectives, Shandong University-Helmholtz Institute of Biotechnology, State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.ORCID 0000-0002-8552-9485
Aiying LiHelmholtz International Lab for Anti-Infectives, Shandong University-Helmholtz Institute of Biotechnology, State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Yajie TangHelmholtz International Lab for Anti-Infectives, Shandong University-Helmholtz Institute of Biotechnology, State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Youming ZhangHelmholtz International Lab for Anti-Infectives, Shandong University-Helmholtz Institute of Biotechnology, State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Xiaoying BianHelmholtz International Lab for Anti-Infectives, Shandong University-Helmholtz Institute of Biotechnology, State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.ORCID 0000-0002-1356-3211
Haibo ZhouHelmholtz International Lab for Anti-Infectives, Shandong University-Helmholtz Institute of Biotechnology, State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.ORCID 0000-0001-9656-6479
Shandong University · CNSoil and Fertilizer Institute of Hunan Province · CN

Funding

111 project B16030Fundamental Research Funds of Shandong University 2019GN029National Key R&D Program of China 2019YFA0905700National Natural Science Foundation of China 32000040, 32070060, 31670098, 31670097Shandong Key Research and Development Program 2019JZZY010724Shandong Provincial Natural Science Foundation ZR2019JQ11
6 · The paper itself

Abstract

The

Indexed as

Biosynthetic PathwaysBurkholderia gladioliGenome, BacterialGenomicsLipopeptidesMultigene FamilyPeptide SynthasesPromoter Regions, GeneticRecombinasesLipopeptidesnon-ribosomal peptide synthasePeptide SynthasesRecombinasesBurkholderiagenome mininglipopeptidespromoter engineeringrecombinase systemsilent biosynthetic gene clusters

Identifiers

PMID33572733
PMCPMC7866175
OpenAlexW3123411726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.