Evidence map›Paper›PMID 33572713›Full record

ReviewMarine drugs2021

Functional and Bioactive Properties of Peptides Derived from Marine Side Streams.

Ilknur Ucak, Maliha Afreen, Domenico Montesano, Celia Carrillo, Igor Tomasevic, Jesus Simal-Gandara, Francisco J Barba

Abstract readReview
In one paragraph

Review in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Functional Food Ingredients Enhancing Immune Health.International journal of molecular sciences · 2025
    Review
  10. Review
  11. Peptide GTSFTTTAER FromFood science & nutrition · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ilknur UcakFaculty of Agricultural Sciences and Technologies, Nigde Omer Halisdemir University, 51000 Nigde, Turkey.
Maliha AfreenFaculty of Agricultural Sciences and Technologies, Nigde Omer Halisdemir University, 51000 Nigde, Turkey.
Domenico MontesanoDepartment of Pharmaceutical Sciences, Section of Food Sciences and Nutrition, University of Perugia, Via S. Costanzo 1, 06126 Perugia, Italy.ORCID 0000-0002-8857-2091
Celia CarrilloNutrition and Food Science, Faculty of Science, Universidad de Burgos, 09001 Burgos, Spain.ORCID 0000-0001-8199-9642
Igor TomasevicDepartment of Animal Source Food Technology, Faculty of Agriculture, University of Belgrade, Nemanjina 6, 11080 Belgrade, Serbia.
Jesus Simal-GandaraNutrition and Bromatology Group, Department of Analytical and Food Chemistry, Faculty of Food Science and Technology, University of Vigo, Ourense Campus, E32004 Ourense, Spain.ORCID 0000-0001-9215-9737
Francisco J BarbaDepartment of Preventive Medicine and Public Health, Food Science, Toxicology and Forensic Medicine, Faculty of Pharmacy, Universitat de València, Avda. Vicent Andrés Estellés, 46100 Burjassot, Spain.ORCID 0000-0002-5630-3989

Funding

European Commission 790956
6 · The paper itself

Abstract

In fish processing, a great amount of side streams, including skin, bones, heads and viscera, is wasted or downgraded as feed on a daily basis. These side streams are rich sources of bioactive nitrogenous compounds and protein, which can be converted into peptides through enzymatic hydrolysis as well as bacterial fermentation. Peptides are short or long chains of amino acids differing in structure and molecular weight. They can be considered as biologically active as they can contribute to physiological functions in organisms with applications in the food and pharmaceutical industries. In the food industry, such bioactive peptides can be used as preservatives or antioxidants to prevent food spoilage. Furthermore, peptides contain several functional qualities that can be exploited as tools in modifying food ingredient solubility, water-holding and fat-binding capacity and gel formation. In the pharmaceutical industry, peptides can be used as antioxidants, but also as antihypertensive, anticoagulant and immunomodulatory compounds, amongst other functions. On the basis of their properties, peptides can thus be used in the development of functional foods and nutraceuticals. This review focuses on the bioactive peptides derived from seafood side streams and discusses their technological properties, biological activities and applications.

Indexed as

AnimalsAntihypertensive AgentsAntioxidantsDietary SupplementsDrug IndustryEmulsionsFood IndustryHumansPeptidesRiversSeafoodSolubilityAntihypertensive AgentsAntioxidantsEmulsionsPeptidesantihypertensiveantioxidantbioactive peptidesfunctional propertiesnutraceuticalsseafood side streams

Identifiers

PMID33572713
PMCPMC7912481

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.