Evidence map›Paper›PMID 33572602›Full record

ArticleInternational journal of molecular sciences2021

Diabetes Induces a Transcriptional Signature in Bone Marrow-Derived CD34

Yuri D'Alessandra, Mattia Chiesa, Vera Vigorelli, Veronica Ricci, Erica Rurali, Angela Raucci, Gualtiero Ivanoe Colombo, Giulio Pompilio, Maria Cristina Vinci

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Transcriptomic Profile of LinBMC genomics · 2024
    Article
  5. Article
  6. Article
  7. Review
  8. Novel Targets for Old and Diseased Hearts.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yuri D'AlessandraUnit of Immunology and Functional Genomics, Centro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Mattia ChiesaUnit of Immunology and Functional Genomics, Centro Cardiologico Monzino IRCCS, 20138 Milan, Italy.ORCID 0000-0001-7427-9954
Vera VigorelliUnit of Vascular Biology and Regenerative Medicine, Centro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Veronica RicciUnit of Immunology and Functional Genomics, Centro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Erica RuraliUnit of Vascular Biology and Regenerative Medicine, Centro Cardiologico Monzino IRCCS, 20138 Milan, Italy.ORCID 0000-0002-7291-5811
Angela RaucciUnit of Experimental Cardio-Oncology and Cardiovascular Aging, Centro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Gualtiero Ivanoe ColomboUnit of Immunology and Functional Genomics, Centro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Giulio PompilioUnit of Vascular Biology and Regenerative Medicine, Centro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Maria Cristina VinciUnit of Vascular Biology and Regenerative Medicine, Centro Cardiologico Monzino IRCCS, 20138 Milan, Italy.
Centro Cardiologico Monzino · ITUniversity of Milan · IT

Funding

Ministero della Salute PE-2011-02348537Ministero della Salute Ricerca Corrente 2019
6 · The paper itself

Abstract

Hematopoietic stem/progenitor cells (HSPCs) participate in cardiovascular (CV) homeostasis and generate different types of blood cells including lymphoid and myeloid cells. Diabetes mellitus (DM) is characterized by chronic increase of pro-inflammatory mediators, which play an important role in the development of CV disease, and increased susceptibility to infections. Here, we aimed to evaluate the impact of DM on the transcriptional profile of HSPCs derived from bone marrow (BM). Total RNA of BM-derived CD34

Indexed as

TranscriptomeAgedAntigens, CD34Blood CellsBone MarrowCardiovascular DiseasesCell DifferentiationCohort StudiesCoronary Artery DiseaseDiabetes ComplicationsFemaleGene Expression ProfilingHematopoietic Stem CellsHumansInflammationLymphocytesAntigens, CD34bone marrowCD34+, transcriptional profilediabeteshematopoietic stem cellsinflammation

Identifiers

PMID33572602
PMCPMC7866997
OpenAlexW3126606833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.