ArticleJournal of clinical medicine2021
Vasoactive-Inotropic Score as an Early Predictor of Mortality in Adult Patients with Sepsis.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Mortality among adult patients with sepsis and septic shock in Korea: a systematic review and meta-analysis.Clinical and experimental emergency medicine · 2023Pooled it
- Vaso-active inotropic scores: Clinical value, pros and cons.JHLT open · 2026Article
- Vasoactive-inotropic score and major cardiovascular events in patients undergoing esophagectomy: a retrospective analysis of intravenous lidocaine and thoracic epidural anesthesia.BMC anesthesiology · 2026Article
- Dynamic changes in vasoactive-inotropic score and their prognostic value in severe sepsis and septic shock patients undergoing polymyxin B hemoperfusion: a real-world Asian ICU cohort study.BMC infectious diseases · 2026Article
- Predictors of health-related quality-of-life after cardiac surgery: findings from the ANesthesiology-QUality-Registry (ANQUR) and frailty-management.BMC anesthesiology · 2026Article
- Blood pressure response index trajectories identify distinct hemodynamic phenotypes and predict mortality in septic shock: a two-database retrospective cohort study.Critical care (London, England) · 2026Article
- Assessment of the vasoactive-inotropic score in prognostic evaluation of critical patients following noncardiac surgery: a retrospective, observational study.BMC anesthesiology · 2026Observational
- Prediction hospital mortality for critical illness lung cancer patients with pneumonia.BMC infectious diseases · 2026Article
- Microbiological and Infection-Source Predictors of Mortality in Severe Sepsis Patients Undergoing Polymyxin B Hemoperfusion: A Seven-Year Real-World Cohort Study.Life (Basel, Switzerland) · 2026Article
- Sequential Versus Non-Sequential Polymyxin B Hemoperfusion in Severe Sepsis and Septic Shock: A Real-World Cohort Analysis of Survival in an Asian ICU.Diagnostics (Basel, Switzerland) · 2026Article
- Vasoactive-Inotropic Score Reduction Rate Is Highly Associated With Prognosis for Critically Ill Patients With Cardiogenic Shock: Insights From the Real-World Dynamic Data.Cardiovascular therapeutics · 2026Observational
- Impact of Continuous Renal Replacement Therapy on Outcomes in Septic Shock Patients Receiving Polymyxin B Hemoperfusion: A Retrospective Cohort Study.Biomedicines · 2025Article
- Article
- Real-World Outcomes and Prognostic Factors of Polymyxin B Hemoperfusion in Severe Sepsis and Septic Shock: A Seven-Year Single-Center Cohort Study from Taiwan.Life (Basel, Switzerland) · 2025Article
- Vasoactive Inotrope Score as a Predictor of Postoperative Complications in Cancer Surgery Patients-A Prospective Observational Study.Indian journal of surgical oncology · 2024Article
- Clinical characteristics and mortality risk factors of premature infants with carbapenem-resistant Klebsiella pneumoniae bloodstream infection.Scientific reports · 2024Article
- Impact of early myocardial injury on patients with severe pneumonia.Internal and emergency medicine · 2024Article
- Lower Levels of Vitamin D Are Associated with Higher Vasoactive-Inotropic Scores in Major Cardiac Surgery.Life (Basel, Switzerland) · 2024Article
- Blood pressure response index and clinical outcomes in patients with septic shock: a multicenter cohort study.EBioMedicine · 2024Article
- A retrospective observational study evaluating the association between vasoactive-inotropic score and mortality after major abdominal surgery.Scientific reports · 2024Observational
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Authors and funding
8 authors.
Funding
Abstract
Vasoactive and inotropic medications are essential for sepsis management; however, the association between the maximum Vasoactive-Inotropic score (VISmax) and clinical outcomes is unknown in adult patients with sepsis. We investigated the VISmax as a predictor for mortality among such patients in the emergency department (ED) and compared its prognostic value with that of the sequential organ failure assessment (SOFA) score. This single-center retrospective study included 910 patients diagnosed with sepsis between January 2016 and March 2020. We calculated the VISmax using the highest doses of vasopressors and inotropes administered during the first 6 h on ED admission and categorized it as 0-5, 6-15, 16-30, 31-45, and >45 points. The primary outcome was 30-day mortality. VISmax for 30-day mortality was significantly higher in non-survivors than in survivors. The mortality rates in the five VISmax groups were 17.2%, 20.8%, 33.3%, 54.6%, and 70.0%, respectively. The optimal cut-off value of VISmax to predict 30-day mortality was 31. VISmax had better prognostic value than the cardiovascular component of the SOFA score and initial lactate levels. VISmax was comparable to the APACHE II score in predicting 30-day mortality. Multivariable analysis showed that VISmax 16-30, 31-45, and >45 were independent risk factors for 30-day mortality. VISmax in ED could help clinicians to identify sepsis patients with poor prognosis.
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