Evidence map›Paper›PMID 33572488›Full record

ArticleNutrients2021

The Potential Contribution of Fortified Maize Flour, Oil, Rice, Salt, and Wheat Flour to Estimated Average Requirements and Tolerable Upper Intake Levels for 15 Nutrients in 153 Countries.

Helena Pachón, Bethany Reynolds, Michelle Duong, Becky L Tsang, Lana Childs, Corey L Luthringer, Yunhee Kang, Florencia C Vasta, Karen Codling

Abstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Barriers and facilitators to the implementation of mandatory folate fortification as an evidence-based policy to prevent neural tube defects.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Helena PachónFood Fortification Initiative, Atlanta, GA 30322, USA.ORCID 0000-0003-0599-3008
Bethany ReynoldsDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Michelle DuongIodine Global Network; P.O. Box 51030, 375 des Epinettes, Ottawa, ON K1E 3E6, Canada.ORCID 0000-0002-2445-7625
Becky L TsangIodine Global Network; P.O. Box 51030, 375 des Epinettes, Ottawa, ON K1E 3E6, Canada.
Lana ChildsFood Fortification Initiative, Atlanta, GA 30322, USA.
Corey L LuthringerIodine Global Network; P.O. Box 51030, 375 des Epinettes, Ottawa, ON K1E 3E6, Canada.
Yunhee KangDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Florencia C VastaGlobal Alliance for Improved Nutrition, 1202 Geneva, Switzerland.
Karen CodlingIodine Global Network; P.O. Box 51030, 375 des Epinettes, Ottawa, ON K1E 3E6, Canada.

Funding

Bill and Melinda Gates Foundation OPP1210398
6 · The paper itself

Abstract

Food fortification is designed to improve the nutritional profile of diets. The purpose of this research was to estimate the potential nutrient contribution of fortified maize flour, oil, rice, salt, and wheat flour in 153 countries, using the national intake (or availability) of the food and the nutrient levels required for fortification. This was done under two scenarios-maximum, where 100% of the food is assumed to be industrially processed and fortified, and realistic, where the maximum value is adjusted based on the percent of the food that is industrially processed and fortified. Under the maximum scenario, the median Estimated Average Requirements (EARs) met ranged from 22-75% for 14 nutrients (vitamins A, B1, B2, B3, B6, B12, D, E, folic acid and calcium, fluoride, iron, selenium and zinc), and 338% for iodine. In the realistic scenario, the median EARs met were 181% for iodine and <35% for the other nutrients. In both scenarios, the median Tolerable Upper Intake Levels (ULs) met were <55% for all nutrients. Under the realistic scenario, no country exceeded 100% of the UL for any nutrient. Current fortification practices of the five foods of interest have the global potential to contribute up to 15 nutrients to the diets of people, with minimal risk of exceeding ULs.

Indexed as

Food, FortifiedOryzaTriticumZea maysEatingFlourHumansMicronutrientsNo-Observed-Adverse-Effect LevelNutritional RequirementsPlant OilsSodium Chloride, DietaryMicronutrientsPlant OilsSodium Chloride, Dietarycondimentsdietary reference intakesenrichmentfortificationmicronutrients

Identifiers

PMID33572488
PMCPMC7916358

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.