Evidence map›Paper›PMID 33572416›Full record

Trial reportInternational journal of environmental research and public health2021

Evaluation of the Use of Sterilized and Non-Sterilized Peruibe Black Mud in Patients with Knee Osteoarthritis.

Paulo Fávio Macedo Gouvêa, Zélia Maria Nogueira Britschka, Cristina de Oliveira Massoco Salles Gomes, Nicolle Gilda Teixeira de Queiroz, Pablo Antonio Vásquez Salvador, Paulo Sergio Cardoso Silva

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Peloids as Thermotherapeutic Agents.International journal of environmental research and public health · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Paulo Fávio Macedo GouvêaEnergy and Nuclear Research Institute, Av. Prof. Lineu Prestes 2242, Cidade Universitária, São Paulo 05508-000, SP, Brazil.
Zélia Maria Nogueira BritschkaEnergy and Nuclear Research Institute, Av. Prof. Lineu Prestes 2242, Cidade Universitária, São Paulo 05508-000, SP, Brazil.
Cristina de Oliveira Massoco Salles GomesDepartment of Pathology, School of Veterinary Medicine and Animal Sciences, University of São Paulo, Av. Prof. Orlando Marques de Paiva, São Paulo 05508-270, SP, Brazil.
Nicolle Gilda Teixeira de QueirozDepartment of Pathology, School of Veterinary Medicine and Animal Sciences, University of São Paulo, Av. Prof. Orlando Marques de Paiva, São Paulo 05508-270, SP, Brazil.
Pablo Antonio Vásquez SalvadorEnergy and Nuclear Research Institute, Av. Prof. Lineu Prestes 2242, Cidade Universitária, São Paulo 05508-000, SP, Brazil.
Paulo Sergio Cardoso SilvaEnergy and Nuclear Research Institute, Av. Prof. Lineu Prestes 2242, Cidade Universitária, São Paulo 05508-000, SP, Brazil.ORCID 0000-0002-9351-9201
Instituto de Pesquisas Energéticas e Nucleares · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate the effects of treatment with Peruíbe Black Mud (PBM) on the clinical parameters and quality of life of patients with knee osteoarthritis and to compare the effects of PBM samples simply matured in seawater and PBM sterilized by gamma radiation. A controlled, double-blind trial was conducted with 41 patients divided into two treatment groups composed of 20 and 21 patients: one group was treated with matured PBM and the other with sterilized PBM. Evaluations were done using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and the Medical Outcomes Study Short Form 36 (SF-36) questionnaires, the Kellgren and Lawrence (KL) radiographic scale, and the quantification of the serum levels of inflammatory biomarkers. An improvement in pain, physical functions, and quality of life was observed in all of the patients who underwent treatment with both simply matured and sterilized PBM. Nine patients showed remission in the KL radiographic scale, but no statistically significant differences were observed in the serum levels of inflammatory mediators before or after treatment. Peruíbe Black Mud proves to be a useful tool as an adjuvant treatment for knee osteoarthritis (OA), as shown by the results of the WOMAC and SF-36 questionnaires and by the remission of the radiographic grade of some patients on the Kellgren and Lawrence scale.

Indexed as

Osteoarthritis, KneeBlack or African AmericanHumansPainPain MeasurementQuality of Lifefangotherapyknee osteoarthritismud therapypeloidPeruíbe Black Mud

Identifiers

PMID33572416
PMCPMC7916169
OpenAlexW3126816134

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.