Evidence map›Paper›PMID 33572077›Full record

ReviewInternational journal of molecular sciences2021

Allosteric Interactions between Adenosine A

Kavya Prasad, Erik F J de Vries, Philip H Elsinga, Rudi A J O Dierckx, Aren van Waarde

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. GPCR heteromers: Beyond the monomeric paradigm in neuropsychiatric drug discovery.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Review
  3. Review
  4. Sialylation in the nervous system: Functions and mechanisms.The Journal of biological chemistry · 2026
    Review
  5. Review
  6. Review
  7. Article
  8. Adenosine AFrontiers in pharmacology · 2026
    Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Dopamine DASN neuro
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kavya PrasadDepartment of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713GZ Groningen, The Netherlands.
Erik F J de VriesDepartment of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713GZ Groningen, The Netherlands.ORCID 0000-0002-6915-1590
Philip H ElsingaDepartment of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713GZ Groningen, The Netherlands.
Rudi A J O DierckxDepartment of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713GZ Groningen, The Netherlands.
Aren van WaardeDepartment of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713GZ Groningen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adenosine and dopamine interact antagonistically in living mammals. These interactions are mediated via adenosine A

Indexed as

Adenosine A2 Receptor AgonistsAdenosine A2 Receptor AntagonistsAllosteric RegulationAnimalsAstrocytesCyclic AMPDisease Models, AnimalGABAergic NeuronsGlobus PallidusHumansLigandsLocomotionMiceMolecular ImagingNucleus AccumbensParkinson DiseaseAdenosine A2 Receptor AgonistsAdenosine A2 Receptor AntagonistsCyclic AMPLigandsReceptor, Adenosine A2AReceptors, Dopamine D2adenosine A2A receptorallosteric interactiondopamine D2 receptorGABAergic enkephalinergic neuronheteromersreceptor–receptor interactionsstriatum

Identifiers

PMID33572077
PMCPMC7915359

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.