Evidence map›Paper›PMID 33571930›Full record

Trial reportGeriatric nursing (New York, N.Y.)

Pain in persons with dementia and the direct and indirect impacts on caregiver burden.

Natalie G Regier, Janiece L Taylor, Sarah L Szanton, Patricia A Parmelee, Nancy Perrin, Minhui Liu, Emerald Jenkins, Nancy A Hodgson, Laura N Gitlin

Open access · greenAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Geriatric nursing (New York, N.Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Natalie G RegierJohns Hopkins University School of Nursing, Baltimore, MD, USA; Johns Hopkins Center for Innovative Care in Aging, Baltimore, MD, USA. Electronic address: Nregier1@jhu.edu.
Janiece L TaylorJohns Hopkins University School of Nursing, Baltimore, MD, USA; Johns Hopkins Center for Innovative Care in Aging, Baltimore, MD, USA.
Sarah L SzantonJohns Hopkins University School of Nursing, Baltimore, MD, USA; Johns Hopkins Center for Innovative Care in Aging, Baltimore, MD, USA; Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Patricia A ParmeleeThe University of Alabama, Alabama Research Institute on Aging, Tuscaloosa, AL, USA.
Nancy PerrinJohns Hopkins University School of Nursing, Baltimore, MD, USA.
Minhui LiuJohns Hopkins University School of Nursing, Baltimore, MD, USA; Johns Hopkins Center for Innovative Care in Aging, Baltimore, MD, USA.
Emerald JenkinsJohns Hopkins University School of Nursing, Baltimore, MD, USA.
Nancy A HodgsonUniversity of Pennsylvania School of Nursing, Philadelphia, PA, USA.
Laura N GitlinJohns Hopkins Center for Innovative Care in Aging, Baltimore, MD, USA; Drexel College of Nursing and Health Professions, Philadelphia, PA, USA.
Johns Hopkins University · USUniversity of Alabama · USUniversity of Pennsylvania · US

Funding

Technological Assessment and Solutions Core - RC4P30AG021334 · NIA · JOHNS HOPKINS UNIVERSITY · PI Jeremy D Walston · 2003 to 2026
$33.2M
Reducing Family Caregiver Upset with Disruptive BehaviorR01AG022254 · NIA · THOMAS JEFFERSON UNIVERSITY · PI GITLIN, LAURA N. · 2002 to 2006
$2.7M
Meaningful Activity Intervention for Individuals With Early-Stage Dementia: Involving the End User in Intervention DesignK23AG058809 · NIA · JOHNS HOPKINS UNIVERSITY · PI REGIER, NATALIE GRACE · 2018 to 2022
$827k
NIA NIH HHS K23 AG058809NIA NIH HHS P30 AG021334NIA NIH HHS R01 AG022254
6 · The paper itself

Abstract

objectivesUnresolved pain is related to neuropsychiatric symptoms (NPS) in persons living with dementia (PLWD), and an increase in NPS is distressing for PLWD and their caregivers. Hence, we examined whether pain in PLWD was related to caregiver burden and whether caregiver upset with NPS mediated this relationship.

methodWe examined, cross-sectionally, the relationships among pain in PLWD, caregiver burden, and upset with NPS. Data from 272 PLWD and their caregivers who participated in the Advancing Caregiver Training (ACT) trial were analyzed using structural equation modeling (SEM).

resultsModel fit was satisfactory, and caregiver upset with NPS fully mediated the association between pain in PLWD and caregiver burden.

conclusionCaregiver upset with NPS helps explain the relationship between pain in PLWD and burden in their caregivers. Pain and NPS are amenable to modification, as is caregiver burden, suggesting great opportunity to impact the lives of PLWD and their caregivers.

Indexed as

Caregiver BurdenDementiaCaregiversHumansPainCaregiver burdenCaregiver upsetDementiaNeuropsychiatric symptomsPain

Identifiers

PMID33571930
PMCPMC8832466
OpenAlexW3126925941

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.