Evidence map›Paper›PMID 33571742›Full record

ReviewEarly human development2021

COVID-19 and developmental origins of health and disease.

Stefano Forestieri, Roberta Pintus, Maria Antonietta Marcialis, Maria Cristina Pintus, Vassilios Fanos

Open access · greenAbstract readReview
In one paragraph

Review in Early human development, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Stefano ForestieriSchool of Pediatrics, University of Cagliari, Cagliari, Italy.
Roberta PintusDepartment of Surgery, Neonatal Intensive Care Unit, University of Cagliari, Cagliari, Italy. Electronic address: gomberta@icloud.com.
Maria Antonietta MarcialisNeonatal Intensive Care Unit, AOU, Cagliari, Cagliari, Italy.
Maria Cristina PintusNeonatal Intensive Care Unit, AOU, Cagliari, Cagliari, Italy.
Vassilios FanosDepartment of Surgery, Neonatal Intensive Care Unit, University of Cagliari, Cagliari, Italy; Neonatal Intensive Care Unit, AOU, Cagliari, Cagliari, Italy.
University of Cagliari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

From the moment of the identification of SARS-CoV-2 as an etiological agent of the severe clinical pictures of pneumonia that were being slowly observed all over the world, numerous studies have been conducted to increase the knowledge about what was an unknown virus until then. The efforts were mainly aimed to acquire epidemiological, microbiological, pathogenetic, clinical, diagnostic, therapeutic and preventive information in order to increase the available weapons to fight an infection which was rapidly taking on the characteristics of the pandemic. Given the topicality of the problem, not everything has yet been fully understood and clarified, especially in the maternal-fetal‑neonatal field, where we are beginning to question what could be the outcomes of newborn babies born to mothers who contracted SARS-CoV-2 infection during pregnancy. Thus, the aim of this review is to analyze the long-term outcomes of this infection that could affect the offspring, regardless of a possible maternal-fetal transmission, focusing on, above all, the role of maternal immune activation and the expression of the Angiotensin-converting enzyme 2 (ACE2) in particular at the placental level.

Indexed as

Adaptive ImmunityAngiotensin-Converting Enzyme 2COVID-19FemaleFetal DevelopmentHumansInfant, NewbornInfant, Newborn, DiseasesInfectious Disease Transmission, VerticalPlacentaPregnancyPregnancy Complications, InfectiousTime FactorsACE2 protein, humanAngiotensin-Converting Enzyme 2ACE2CoronavirusCOVID-19DOHaDMaternal immune activationMIANeuropsychiatric disordersOffspringSARS-CoV-2

Identifiers

PMID33571742
PMCPMC7837628
OpenAlexW3124941532

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.