Observational studyOphthalmology2021
Alcohol Consumption and Incident Cataract Surgery in Two Large UK Cohorts.
Observational study in Ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 31 citations in OpenAlex.
- Determinants of Pentacam-derived lens density in age-related cataract: the role of ocular dominance and lifestyle factors.BMC ophthalmology · 2026Article
- T1D-Related Cataract Risk Amplification: Mendelian Randomisation Confirms a Dual Hit of Immune-Inflammatory Burden and Metabolic Stress.Combinatorial chemistry & high throughput screening · 2026Article
- Risk factors for self-reports of diagnosed cataracts among older adults in Poland.BMC public health · 2025Article
- Predictors of Cataract Surgery Among US Adults: NHANES 2007-2008.Healthcare (Basel, Switzerland) · 2025Article
- Sex-specific social, lifestyle, and physical health risk factors in cataracts development.Eye (London, England) · 2024Article
- Predictors and consequences of visual trajectories in Chinese older population: A growth mixture model.Journal of global health · 2024Article
- Association of age at diagnosis of diabetes with subsequent risk of age-related ocular diseases and vision acuity.World journal of diabetes · 2024Article
- Using genetics to investigate the association between lanosterol and cataract.Frontiers in genetics · 2024Article
- Association of autoimmune and allergic diseases with senile cataract: a bidirectional two-sample Mendelian randomization study.Frontiers in immunology · 2024Article
- Is Occasional Alcohol Drinking and Smoking Related to the Development of Age-Related Cataract?Investigative ophthalmology & visual science · 2023Article
- Association of Behavioral and Clinical Risk Factors With Cataract: A Two-Sample Mendelian Randomization Study.Investigative ophthalmology & visual science · 2023Article
- Alcohol use patterns and risk of incident cataract surgery: a large scale case-control study in Japan.Scientific reports · 2022Article
- Beer, wine, and spirits differentially influence body composition in older white adults-a United Kingdom Biobank study.Obesity science & practice · 2022Article
- Cross-sectional study of the association between asthma and cataract among 40 years and older in the USA.BMC ophthalmology · 2022Article
- Associations of Alcohol Consumption and Smoking With Disease Risk and Neurodegeneration in Individuals With Multiple Sclerosis in the United Kingdom.JAMA network open · 2022Article
- Metabolic and lifestyle factors in relation to senile cataract: a Mendelian randomization study.Scientific reports · 2022Article
- Risk of inflammatory bowel disease appears to vary across different frequency, amount, and subtype of alcoholic beverages.Frontiers in nutrition · 2022Article
- Adiposity by Differing Measures and the Risk of Cataract in the UK Biobank: The Importance of Diabetes.Investigative ophthalmology & visual science · 2021Article
- COVID-19 Risk Appears to Vary Across Different Alcoholic Beverages.Frontiers in nutrition · 2021Article
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Authors and funding
14 authors at 4 institutions in 1 country.
Funding
Abstract
purposeTo examine the association of alcohol consumption and type of alcoholic beverage with incident cataract surgery in 2 large cohorts.
designLongitudinal, observational study.
participantsWe included 469 387 participants of UK Biobank with a mean age of 56 years and 23 162 participants of European Prospective Investigation of Cancer (EPIC)-Norfolk with a mean age of 59 years.
methodsSelf-reported alcohol consumption at baseline was ascertained by a touchscreen questionnaire in UK Biobank and a food-frequency questionnaire in EPIC-Norfolk. Cases were defined as participants undergoing cataract surgery in either eye as ascertained via data linkage to National Health Service procedure statistics. We excluded participants with cataract surgery up to 1 year after the baseline assessment visit or those with self-reported cataract at baseline. Cox proportional hazards models were used to examine the associations of alcohol consumption with incident cataract surgery, adjusted for age, sex, ethnicity, Townsend deprivation index, body mass index (BMI), smoking, and diabetes status.
main outcome measuresIncident cataract surgery.
resultsThere were 19 011 (mean cohort follow-up of 95 months) and 4573 (mean cohort follow-up of 193 months) incident cases of cataract surgery in UK Biobank and EPIC-Norfolk, respectively. Compared with nondrinkers, drinkers were less likely to undergo cataract surgery in UK Biobank (hazard ratio [HR], 0.89; 95% confidence interval [CI], 0.85-0.93) and EPIC-Norfolk (HR, 0.90; 95% CI, 0.84-0.97) after adjusting for covariables. Among alcohol consumers, greater alcohol consumption was associated with a reduced risk of undergoing cataract surgery in EPIC-Norfolk (P < 0.001), whereas a U-shaped association was observed in the UK Biobank. Compared with nondrinkers, subgroup analysis by type of alcohol beverage showed the strongest protective association with wine consumption; the risk of incident cataract surgery was 23% and 14% lower among those in the highest category of wine consumption in EPIC-Norfolk and UK Biobank, respectively.
conclusionsOur findings suggest a lower risk of undergoing cataract surgery with low to moderate alcohol consumption. The association was particularly apparent with wine consumption. We cannot exclude the possibility of residual confounding, and further studies are required to determine whether this association is causal in nature.
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