Evidence map›Paper›PMID 33571475›Full record

ArticleAmerican journal of ophthalmology2021

Impact of Visual Field Loss on Vision-Specific Quality of Life in African Americans: The African American Eye Disease Study.

Dominic J Grisafe, Rohit Varma, Bruce S Burkemper, Benjamin Y Xu, Mina Torres, Alicia Fairbrother-Crisp, Cecilia M Patino, Roberta McKean-Cowdin, African American Eye Disease Study Group

Open access · greenAbstract read
In one paragraph

Article in American journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Dominic J GrisafeFrom the Department of Preventive Medicine and the Roski Eye Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.
Rohit VarmaSouthern California Eye Institute, CHA Hollywood Presbyterian Medical Center, Los Angeles, California, USA. Electronic address: rvarma@sceyes.org.
Bruce S BurkemperDepartment of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.
Benjamin Y XuDepartment of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.
Mina TorresSouthern California Eye Institute, CHA Hollywood Presbyterian Medical Center, Los Angeles, California, USA.
Alicia Fairbrother-CrispSouthern California Eye Institute, CHA Hollywood Presbyterian Medical Center, Los Angeles, California, USA.
Cecilia M PatinoFrom the Department of Preventive Medicine and the Roski Eye Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.
Roberta McKean-CowdinFrom the Department of Preventive Medicine and the Roski Eye Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.
African American Eye Disease Study Group
University of Southern California · USPenn Presbyterian Medical Center · US

Funding

Translational Research Support CoreP30ES007048 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ROB S MCCONNELL · 1996 to 2026
$46.4M
RESEARCH TRAINING IN GERONTOLOGYT32AG000037 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JENNIFER A AILSHIRE, EILEEN M CRIMMINS · 1985 to 2026
$13.2M
African American Eye Disease StudyU10EY023575 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI VARMA, ROHIT · 2013 to 2017
$12.1M
Training Grant in Genomic Analysis and InterpretationT32ES013678 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GAUDERMAN, WILLIAM JAMES, MCCONNELL, ROB S · 2006 to 2023
$5.6M
NEI NIH HHS U10 EY023575NIA NIH HHS T32 AG000037NIEHS NIH HHS P30 ES007048NIEHS NIH HHS T32 ES013678
6 · The paper itself

Abstract

purposeTo elucidate how visual field loss (VFL) impacts self-reported vision-specific quality of life (VSQOL) in African Americans, who experience a disproportionate burden of visual impairment.

designCross-sectional, population-based cohort.

methodsEligible participants (n = 7,957) were recruited who self-identified as African American, were aged 40 years or older, and resided in Inglewood, California, USA. A total of 6,347 participants (80.0%) completed clinical eye examinations. Total mean deviation (MD) of VFL was measured bilaterally as decibels (dB) using the Humphrey SITA Standard 24-2 test. VSQOL was measured using the National Eye Institute Visual Function Questionnaire (NEI-VFQ 25) and scored using item response theory (IRT).

resultsParticipants with reliable data (n = 5,121) had a mean age of 60.7 years (standard deviation 11.0); those with worse VFL were older; had more comorbidities, lower income, less education, and worse visual acuity; and were more likely to be unemployed and depressed. Using IRT analysis, a change in VF of 6.2 (95% confidence interval [CI]: 5.3, 7.7) dB and 9.2 (95% CI: 7.5, 11.9) dB was necessary to observe a meaningful (5-point) difference in vision-related task and emotional well-being scores, respectively. VFL had the greatest impact on self-reported driving ability (6.0 dB [95% CI: 5.2, 7.1]), followed by satisfaction with general vision, near vision, vision-related mental health, and peripheral vision.

conclusionsThe strongest impact of VFL reported by African Americans was on their ability to complete visual tasks, especially for driving. An effect of VFL on emotional well-being also was observed, but the magnitude of association was about 50% lower for well-being compared to that of task.

Indexed as

Black or African AmericanQuality of LifeCross-Sectional StudiesHumansMiddle AgedSickness Impact ProfileSurveys and QuestionnairesVision DisordersVisual Fields

Identifiers

PMID33571475
PMCPMC8349371
OpenAlexW3128609411

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.