Evidence map›Paper›PMID 33571010›Full record

ArticleThe British journal of radiology2021

Low-dose whole-body CT using deep learning image reconstruction: image quality and lesion detection.

Yoshifumi Noda, Tetsuro Kaga, Nobuyuki Kawai, Toshiharu Miyoshi, Hiroshi Kawada, Fuminori Hyodo, Avinash Kambadakone, Masayuki Matsuo

Open access · greenAbstract read
In one paragraph

Article in The British journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

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  12. Systematic Review on Learning-based Spectral CT.IEEE transactions on radiation and plasma medical sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Yoshifumi NodaDepartment of Radiology, Gifu University, 1-1 Yanagido, Gifu 501-1194, Japan.
Tetsuro KagaDepartment of Radiology, Gifu University, 1-1 Yanagido, Gifu 501-1194, Japan.
Nobuyuki KawaiDepartment of Radiology, Gifu University, 1-1 Yanagido, Gifu 501-1194, Japan.
Toshiharu MiyoshiDepartment of Radiology, Gifu University, 1-1 Yanagido, Gifu 501-1194, Japan.
Hiroshi KawadaDepartment of Radiology, Gifu University, 1-1 Yanagido, Gifu 501-1194, Japan.
Fuminori HyodoDepartment of Radiology, Frontier Science for Imaging, Gifu University, 1-1 Yanagido, Gifu 501-1194, Japan.
Avinash KambadakoneDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Masayuki MatsuoDepartment of Radiology, Gifu University, 1-1 Yanagido, Gifu 501-1194, Japan.
Gifu University · JPMassachusetts General Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate image quality and lesion detection capabilities of low-dose (LD) portal venous phase whole-body computed tomography (CT) using deep learning image reconstruction (DLIR).

methodsThe study cohort of 59 consecutive patients (mean age, 67.2 years) who underwent whole-body LD CT and a prior standard-dose (SD) CT reconstructed with hybrid iterative reconstruction (SD-IR) within one year for surveillance of malignancy were assessed. The LD CT images were reconstructed with hybrid iterative reconstruction of 40% (LD-IR) and DLIR (LD-DLIR). The radiologists independently evaluated image quality (5-point scale) and lesion detection. Attenuation values in Hounsfield units (HU) of the liver, pancreas, spleen, abdominal aorta, and portal vein; the background noise and signal-to-noise ratio (SNR) of the liver, pancreas, and spleen were calculated. Qualitative and quantitative parameters were compared between the SD-IR, LD-IR, and LD-DLIR images. The CT dose-index volumes (CTDI

resultsThe image quality and lesion detection rate of the LD-DLIR was comparable to the SD-IR. The image quality was significantly better in SD-IR than in LD-IR (

conclusionLD CT images reconstructed with DLIR enable radiation dose reduction of >75% while maintaining image quality and lesion detection rate and superior SNR in comparison to SD-IR. ADVANCES IN KNOWLEDGE: Deep learning image reconstruction algorithm enables around 80% reduction in radiation dose while maintaining the image quality and lesion detection compared to standard-dose whole-body CT.

Indexed as

Deep LearningAdultAgedAged, 80 and overAlgorithmsContrast MediaFemaleHumansMaleMiddle AgedNeoplasmsPostoperative PeriodProspective StudiesQuality ControlRadiation DosageRadiographic Image Interpretation, Computer-AssistedContrast Media

Identifiers

PMID33571010
PMCPMC8506192
OpenAlexW3128421565

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.