Evidence map›Paper›PMID 33570901›Full record

ArticleACS nano2021

Gold Nanocomposite Contact Lenses for Color Blindness Management.

Ahmed E Salih, Mohamed Elsherif, Fahad Alam, Ali K Yetisen, Haider Butt

Open access · hybridAbstract read
In one paragraph

Article in ACS nano, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 95 citations in OpenAlex.

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  8. RSC advances · 2025
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  20. 3D Printing of Multimaterial Contact Lenses.ACS biomaterials science & engineering · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Ahmed E SalihDepartment of Mechanical Engineering, Khalifa University, Abu Dhabi, United Arab Emirates.
Mohamed ElsherifDepartment of Mechanical Engineering, Khalifa University, Abu Dhabi, United Arab Emirates.
Fahad AlamDepartment of Mechanical Engineering, Khalifa University, Abu Dhabi, United Arab Emirates.
Ali K YetisenDepartment of Chemical Engineering, Imperial College London, London SW7 2AZ, United Kingdom.ORCID 0000-0003-0896-267X
Haider ButtDepartment of Mechanical Engineering, Khalifa University, Abu Dhabi, United Arab Emirates.ORCID 0000-0003-2434-9525
Khalifa University of Science and Technology · AEImperial College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Color vision deficiency (CVD) is an ocular congenital disorder that affects 8% of males and 0.5% of females. The most prevalent form of color vision deficiency (color blindness) affects protans and deutans and is more commonly known as "red-green color blindness". Since there is no cure for this disorder, CVD patients opt for wearables that aid in enhancing their color perception. The most common wearable used by CVD patients is a form of tinted glass/lens. Those glasses filter out the problematic wavelengths (540-580 nm) for the red-green CVD patients using organic dyes. However, few studies have addressed the fabrication of contact lenses for color vision deficiency, and several problems related to their effectiveness and toxicity were reported. In this study, gold nanoparticles are integrated into contact lens material, thus forming nanocomposite contact lenses targeted for red-green CVD application. Three distinct sets of nanoparticles were characterized and incorporated with the hydrogel material of the lenses (pHEMA), and their resulting optical and material properties were assessed. The transmission spectra of the developed nanocomposite lenses were analogous to those of the commercial CVD wearables, and their water retention and wettability capabilities were superior to those in some of the commercially available contact lenses used for cosmetic/vision correction purposes. Hence, this work demonstrates the potential of gold nanocomposite lenses in CVD management and, more generally, color filtering applications.

Indexed as

Color Vision DefectsContact LensesMetal NanoparticlesNanocompositesColorFemaleGoldHumansMaleGoldbiomaterialscolor blindnesscontact lensesnanocompositeswearables

Identifiers

PMID33570901
PMCPMC8023801
OpenAlexW3129143531

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.