Evidence map›Paper›PMID 33570807›Full record

ReviewThe FEBS journal2022

C. elegans as a model to study glial development.

Albert Zhang, Dong Yan

Open access · greenAbstract readReview
In one paragraph

Review in The FEBS journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Albert ZhangDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC, USA.
Dong YanDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC, USA.ORCID 0000-0002-7542-1251
Duke Medical Center · USDuke University Hospital · US

Funding

Genetic study of gap junction formation and regulation in C. elegans neuronsR01NS105638 · NINDS · DUKE UNIVERSITY · PI YAN, DONG · 2018 to 2022
$1.8M
Mechanisms of neural circuit formation in C. elegansR01NS094171 · NINDS · DUKE UNIVERSITY · PI YAN, DONG · 2015 to 2019
$1.5M
NINDS NIH HHS R01 NS094171NINDS NIH HHS R01 NS105638
6 · The paper itself

Abstract

Glia make up roughly half of all cells in the mammalian nervous system and play a major part in nervous system development, function, and disease. Although research in the past few decades has shed light on their morphological and functional diversity, there is still much to be known about key aspects of their development such as the generation of glial diversity and the factors governing proper morphogenesis. Glia of the nematode C. elegans possess many developmental and morphological similarities with their vertebrate counterparts and can potentially be used as a model to understand certain aspects of glial biology owing to advantages such as its genetic tractability and fully mapped cell lineage. In this review, we summarize recent progress in our understanding of genetic pathways that regulate glial development in C. elegans and discuss how some of these findings may be conserved.

Indexed as

Caenorhabditis elegansNematodaAnimalsMammalsNeurogenesisNeurogliaVertebratesC. elegansdevelopmentgliagliogenesismorphogenesis

Identifiers

PMID33570807
PMCPMC8355251
OpenAlexW3128588092

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.