ArticleZeitschrift fur Gerontologie und Geriatrie2022
[Identification of polypharmacy-associated risks among nursing home residents].
Article in Zeitschrift fur Gerontologie und Geriatrie, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- [Medication supply and polypharmacy in long-term care : An overview of possible interventions and the question of a functioning concept].Zeitschrift fur Gerontologie und Geriatrie · 2025Review
- [Estimation of the risk of drug-related problems in nursing home residents : A retrospective analysis of routine data].Zeitschrift fur Gerontologie und Geriatrie · 2023Article
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5 authors.
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Abstract
introductionMultimorbidity in old age is one reason for intensified pharmacotherapy. At the same time, an increase in medications could augment multimorbidity, especially when drug interactions leading to undesired drug effects occur.
methodsIn this cross-sectional study 918 mentally ill seniors living in nursing homes (mean age 79.3 (±11.6) years; 31.8% male) were included. Two different approaches to assess risks due to pharmacotherapy were applied: first mediQ, an online-based clinical decision support software (CDSS) and the PRISCUS list, which indicates potentially inappropriate medication. PRISCUS is the German equivalent to the American Geriatrics Society Beers criteria.
resultsOf the patients in the study 76.3% were at clinical risk, 2.2% at potentially high risk for drug interactions regarding the entire medication as tested by mediQ, and about 25% of the studied population received potentially inappropriate medication according to the PRISCUS list.
conclusionThis difference clearly underlines the cumbersome complexity of identifying patients at risk by using these exemplary devices. The focus of avoiding undesired drug side effects should be taking medication only after thorough verification of clinical indications and under close monitoring. The CDSS or negative lists may support this process.
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