Evidence map›Paper›PMID 33570414›Full record

ArticleOrganic letters2021

Suzuki Coupling of Protected Aryl Diazonium Ions: Expanding the Knowledge of Triazabutadiene Compatible Reactions.

Abigail J Shepard, Julia A Townsend, Christopher Foley, Christopher Hulme, Michael T Marty, John C Jewett

Abstract read
In one paragraph

Article in Organic letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Abigail J ShepardDepartment of Pharmacology and Toxicology, University of Arizona, Tucson, Arizona 85721, United States.
Julia A TownsendDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona 85721, United States.
Christopher FoleyDepartment of Pharmacology and Toxicology, University of Arizona, Tucson, Arizona 85721, United States.ORCID 0000-0002-9028-5841
Christopher HulmeDepartment of Pharmacology and Toxicology, University of Arizona, Tucson, Arizona 85721, United States.ORCID 0000-0001-6602-9613
Michael T MartyDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona 85721, United States.ORCID 0000-0001-8115-1772
John C JewettDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona 85721, United States.ORCID 0000-0001-5822-4080

Funding

CHEMISTRY-BIOLOGY INTERFACE TRAINING PROGRAMT32GM008804 · NIGMS · UNIVERSITY OF ARIZONA · PI MONTFORT, WILLIAM R. · 2003 to 2023
$3.9M
Unravelling Membrane Protein-Lipid Interactions using Nanodiscs and Mass SpectrometryR35GM128624 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI Michael T Marty · 2018 to 2026
$3.6M
NIGMS NIH HHS R35 GM128624NIGMS NIH HHS T32 GM008804
6 · The paper itself

Abstract

Aryl diazonium ions are important in synthesis and chemical biology, and the acid-labile triazabutadiene can protect this handle for future use. We report a Suzuki coupling strategy that is compatible with the triazabutadiene scaffold, expanding the scope of synthetically available triazabutadienes. Shown herein, the triazabutadiene scaffold remains intact and reactive after coupling, as demonstrated by releasing the aryl diazonium ion to label a tyrosine-rich model protein.

Indexed as

Diazonium CompoundsIonsMolecular StructureProteinsDiazonium CompoundsIonsProteins

Identifiers

PMID33570414
PMCPMC7955896

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.