Evidence map›Paper›PMID 33569984›Full record

ArticleFuture microbiology2021

Dual targeting of Toll-like receptor 4 and angiotensin-converting enzyme 2: a proposed approach to SARS-CoV-2 treatment.

Laura Kate Gadanec, Tawar Qaradakhi, Kristen Renee McSweeney, Benazir Ashiana Ali, Anthony Zulli, Vasso Apostolopoulos

Abstract readEditorial
In one paragraph

Article in Future microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Phytocompounds of Honey mesquite (In silico pharmacology · 2025
    Article
  2. Review
  3. Article
  4. Review
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  6. Cancer Patients during COVID-19 Pandemic: A Mini-Review.Healthcare (Basel, Switzerland) · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
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  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Laura Kate GadanecInstitute for Health & Sport, Victoria University, Melbourne, Australia.ORCID 0000-0002-4801-8061
Tawar QaradakhiInstitute for Health & Sport, Victoria University, Melbourne, Australia.
Kristen Renee McSweeneyInstitute for Health & Sport, Victoria University, Melbourne, Australia.ORCID 0000-0003-4146-8251
Benazir Ashiana AliInstitute for Health & Sport, Victoria University, Melbourne, Australia.
Anthony ZulliInstitute for Health & Sport, Victoria University, Melbourne, Australia.
Vasso ApostolopoulosInstitute for Health & Sport, Victoria University, Melbourne, Australia.ORCID 0000-0001-6788-2771

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19 Drug TreatmentAngiotensin-Converting Enzyme 2Anti-Inflammatory AgentsAntiviral AgentsCOVID-19Enzyme ActivatorsHumansInflammationMolecular Targeted TherapySARS-CoV-2SulfonamidesToll-Like Receptor 4ACE2 protein, humanAngiotensin-Converting Enzyme 2Anti-Inflammatory AgentsAntiviral AgentsEnzyme Activatorsethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylateSulfonamidesTLR4 protein, humanToll-Like Receptor 4ACE2angiotensin-converting enzyme 2coronaviruscoronavirus disease 2019COVID-19SARS-CoV-2TLR4Toll-like receptor

Identifiers

PMID33569984
PMCPMC7885526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.