ArticleEuropean radiology2021
Gastric poorly cohesive carcinoma: differentiation from tubular adenocarcinoma using nomograms based on CT findings in the 40 s late arterial phase.
Article in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 18 citations in OpenAlex.
- Dual-energy CT to evaluate the infiltration status of tumor-associated macrophage (TAM) in gastric cancer: a preliminary study.Abdominal radiology (New York) · 2026Article
- Noninvasive evaluation of treatment-related protein expression status in advanced gastric cancer using dynamic nomograms with dual-energy CT: a multicenter study.European radiology · 2026Article
- A nomogram model based on CT-assessed body composition parameters for predicting postoperative recurrence in advanced gastric cancer.Abdominal radiology (New York) · 2026Article
- Predictive value of multivariate models combining CT-based extracellular volume fraction with clinicopathological parameters for preoperative detection of occult lymph node metastasis in gastric cancer.Insights into imaging · 2025Article
- Dual-energy CT for predicting serosal invasion in gastric cancer and subtype analysis.Abdominal radiology (New York) · 2025Article
- Epstein-Barr virus positive gastric cancer: the pathological basis of CT findings and radiomics models prediction.Abdominal radiology (New York) · 2024Article
- The role of computed tomography features in assessing response to neoadjuvant chemotherapy in locally advanced gastric cancer.BMC cancer · 2023Article
- Gastric Cancer (GC) with Peritoneal Metastases (PMs): An Overview of Italian PSM Oncoteam Evidence and Study Purposes.Cancers · 2023Review
- Construction of a nomogram predictive model for patients with liver rupture undergoing surgical intervention.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2023Article
- Application of preoperative CT texture analysis in papillary gastric adenocarcinoma.BMC cancer · 2022Article
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7 authors at 1 institution in 1 country.
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Abstract
objectivesTo summarise the CT findings of gastric poorly cohesive carcinoma (PCC) in the 40 s late arterial phase and differentiate it from tubular adenocarcinoma (TAC) using an integrative nomogram.
methodsA total of 241 patients including 59 PCCs, 109 TACs, and 73 other type gastric cancers were enrolled. Thirteen CT morphological characteristics of each lesion in the late arterial phase were evaluated. In addition, CT value-related parameters were extracted from ROIs encompassing the area of greatest enhancement on four-phase CT images. Nomograms based on regression models were built to discriminate PCCs from TACs and from non-PCCs. ROC curve analysis was performed to assess the diagnostic efficiency.
resultsSix morphological characteristics, 10 CT value-related parameters, and the enhanced curve types differed significantly among the above three groups in the primary cohort (all p < 0.05). The paired comparison revealed that 10 CT value-related parameters differed significantly between PCCs and TACs (all p < 0.05). The AUC of the nomogram based on the multivariate model for discriminating PCCs from TACs was 0.954, which was confirmed in the validation cohort (AUC = 0.895). The AUC of another nomogram for discriminating PCCs from non-PCCs was 0.938, which was confirmed in the validation cohort (AUC = 0.880).
conclusionsIn the 40 s late arterial phase, the morphological characteristics and CT value-related parameters were significantly different among PCCs, TACs, and other types. PCCs were prone to manifest mucosal line interruption, diffuse thickening, infiltrative growth, and slow-rising enhanced curve (Type A). Furthermore, multivariate models were useful in discriminating PCCs from TACs and other types. KEY POINTS: • Multiple morphological characteristics and CT value-related parameters differed significantly between gastric PCCs and TACs in the 40 s late arterial phase. • The nomogram integrating morphological characteristics and CT value-related parameters in the 40 s late arterial phase had favourable performance in discriminating PCCs from TACs. • More useful information can be derived from 40 s late arterial phase CT images; thus, a more accurate evaluation can be made in clinical practice.
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