ArticleERJ open research2021
Unilateral diaphragmatic paralysis: inspiratory muscles, breathlessness and exercise capacity.
Article in ERJ open research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 15 citations in OpenAlex.
- Respiratory consequences of cervical spinal cord injury: insights from preclinical models.Breathe (Sheffield, England) · 2026Review
- A Case Series on Unilateral Elevation of Diaphragm.Maedica · 2026Article
- Pattern of extra-diaphragmatic respiratory muscle activity during exercise in patients with unilateral diaphragm dysfunction.Physiological reports · 2025Article
- Exploring the relationship between movement and breathing regulation in Tai Chi practice among middle-aged and older men using a three-dimensional respiratory-movement model.Frontiers in sports and active living · 2025Article
- Article
- Inspiratory muscle training for diaphragmatic dysfunction: A case series.Respiratory medicine case reports · 2024Article
- Post-Myocardial Infarction Rehabilitation: The Absence in the Rehabilitation Process of the Diaphragm Muscle.International journal of general medicine · 2024Review
- Diaphragm and Lung Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2024Review
- Effects of inspiratory muscle training on exertional breathlessness in patients with unilateral diaphragm dysfunction: a randomised trial.ERJ open research · 2023Article
- Measurements of respiratory muscle function as diagnostic criteria for diaphragmatic paralysis.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2021Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with unilateral diaphragmatic paralysis (UDP) may present with dyspnoea without specific cause and limited ability to exercise. We aimed to investigate the diaphragm contraction mechanisms and nondiaphragmatic inspiratory muscle activation during exercise in patients with UDP, compared with healthy individuals.
methodsPulmonary function, as well as volitional and nonvolitional inspiratory muscle strength were evaluated in 35 patients and in 20 healthy subjects. Respiratory pressures and electromyography of scalene and sternocleidomastoid muscles were continuously recorded during incremental maximal cardiopulmonary exercise testing until symptom limitation. Dyspnoea was assessed at rest, every 2 min during exercise and at the end of exercise with a modified Borg scale. MAIN
resultsInspiratory muscle strength measurements were significantly lower for patients in comparison to controls (all p<0.05). Patients achieved lower peak of exercise (lower oxygen consumption) compared to controls, with both gastric (-9.8±4.6 cmH
conclusionThe paralysis group presented with exercise limitation accompanied by impairment in transdiaphragmatic pressure generation and larger accessory inspiratory muscles activation compared to controls, thereby contributing to a neuromechanical dissociation and increased dyspnoea perception.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.