Evidence map›Paper›PMID 33569052›Full record

ArticleFrontiers in immunology2020

Efficient Tissue Clearing and Multi-Organ Volumetric Imaging Enable Quantitative Visualization of Sparse Immune Cell Populations During Inflammation.

Julian Hofmann, Iana Gadjalova, Ritu Mishra, Jürgen Ruland, Selina J Keppler

Abstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julian HofmannInstitute for Clinical Chemistry and Pathobiochemistry, München rechts der Isar (MRI), Technical University Munich, Munich, Germany.
Iana GadjalovaInstitute for Clinical Chemistry and Pathobiochemistry, München rechts der Isar (MRI), Technical University Munich, Munich, Germany.
Ritu MishraInstitute for Clinical Chemistry and Pathobiochemistry, München rechts der Isar (MRI), Technical University Munich, Munich, Germany.
Jürgen RulandInstitute for Clinical Chemistry and Pathobiochemistry, München rechts der Isar (MRI), Technical University Munich, Munich, Germany.
Selina J KepplerInstitute for Clinical Chemistry and Pathobiochemistry, München rechts der Isar (MRI), Technical University Munich, Munich, Germany.

Funding

European Research Council 322865
6 · The paper itself

Abstract

Spatial information of cells in their tissue microenvironment is necessary to understand the complexity of pathophysiological processes. Volumetric imaging of cleared organs provides this information; however, current protocols are often elaborate, expensive, and organ specific. We developed a simplified, cost-effective, non-hazardous approach for

Indexed as

Imaging, Three-DimensionalKidney GlomerulusAnimalsInflammationMiceMicroscopy, ConfocalNephritis3D imagingethyl 3-phenyl-2-propenoate (ECI)glomerulonephritishisto-cytometryinflammation

Identifiers

PMID33569052
PMCPMC7869862

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.