Evidence map›Paper›PMID 33568904›Full record

ArticleInternational journal of chronic obstructive pulmonary disease

Eccentric Left Ventricular Hypertrophy and Left and Right Cardiac Function in Chronic Heart Failure with or without Coexisting COPD: Impact on Exercise Performance.

Polliana B Dos Santos, Rodrigo P Simões, Cássia da L Goulart, Meliza G Roscani, Renan S Marinho, Patrícia Faria Camargo, Renata F Arbex, Guilherme Casale, Cláudio R Oliveira, Renata G Mendes and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of chronic obstructive pulmonary disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. CPET Characteristics in HFrEF, HFpEF and COPD.Journal of clinical medicine · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Utility of Cardiopulmonary Exercise Testing in Chronic Obstructive Pulmonary Disease: A Review.International journal of chronic obstructive pulmonary disease · 2023
    Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Polliana B Dos SantosCardiopulmonary Physical Therapy Laboratory, Federal University of Sao Carlos, Sao Carlos, Brazil.ORCID 0000-0003-3354-8913
Rodrigo P SimõesCardiopulmonary Physical Therapy Laboratory, Federal University of Sao Carlos, Sao Carlos, Brazil.ORCID 0000-0002-7072-0252
Cássia da L GoulartCardiopulmonary Physical Therapy Laboratory, Federal University of Sao Carlos, Sao Carlos, Brazil.ORCID 0000-0001-8731-689X
Meliza G RoscaniDepartment of Medicine, Federal University of Sao Carlos, Sao Carlos, Brazil.ORCID 0000-0003-1463-551X
Renan S MarinhoCardiopulmonary Physical Therapy Laboratory, Federal University of Sao Carlos, Sao Carlos, Brazil.ORCID 0000-0003-4768-8319
Patrícia Faria CamargoCardiopulmonary Physical Therapy Laboratory, Federal University of Sao Carlos, Sao Carlos, Brazil.ORCID 0000-0002-6564-1672
Renata F ArbexCardiopulmonary Physical Therapy Laboratory, Federal University of Sao Carlos, Sao Carlos, Brazil.
Guilherme CasaleDepartment of Medicine, Federal University of Sao Carlos, Sao Carlos, Brazil.
Cláudio R OliveiraDepartment of Medicine, Federal University of Sao Carlos, Sao Carlos, Brazil.ORCID 0000-0001-6154-3488
Renata G MendesCardiopulmonary Physical Therapy Laboratory, Federal University of Sao Carlos, Sao Carlos, Brazil.ORCID 0000-0003-4683-2657
Ross ArenaDepartment of Physical Therapy, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, USA.
Audrey Borghi-SilvaCardiopulmonary Physical Therapy Laboratory, Federal University of Sao Carlos, Sao Carlos, Brazil.ORCID 0000-0002-3891-6941
Universidade Federal de São Carlos · BRUniversity of Illinois Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimOur aim was to assess: 1) the impact of the eccentric left ventricular hypertrophy (ELVH) on exercise performance in patients diagnosed with chronic heart failure (CHF) alone and in patients with co-existing CHF and chronic obstructive pulmonary disease (COPD) and 2) the relationship between left and right cardiac function measurements obtained by doppler echocardiography, clinical characteristics and primary measures of cardiorespiratory fitness.

methodsThe current study included 46 patients (CHF:23 and CHF+COPD:23) that performed advanced pulmonary function tests, echocardiography and symptom-limited, incremental cardiopulmonary exercise testing (CPET) on a cycle ergometer.

resultsPatients with CHF+COPD demonstrated a lower work rate, peak oxygen uptake (VO

conclusionCompared to a diagnosis of CHF alone, a combined diagnosis of CHF+COPD induced further impairments in cardiorespiratory fitness. Moreover, echocardiographic measures of cardiac function are related to cardiopulmonary exercise performance and therefore appear to be an important therapeutic target when attempting to improve exercise performance and functional capacity.

Indexed as

Heart FailurePulmonary Disease, Chronic ObstructiveExercise TestExercise ToleranceHumansHypertrophy, Left VentricularOxygen ConsumptionVentricular Function, Leftcardiopulmonary exercise testingchronic obstructive pulmonary diseaseeccentric hypertrophyechocardiographyheart failureventricular dysfunction

Identifiers

PMID33568904
PMCPMC7868200
OpenAlexW3128398672

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.