Evidence map›Paper›PMID 33568816›Full record

ArticleNature2021

Non-coding deletions identify Maenli lncRNA as a limb-specific En1 regulator.

Lila Allou, Sara Balzano, Andreas Magg, Mathieu Quinodoz, Beryl Royer-Bertrand, Robert Schöpflin, Wing-Lee Chan, Carlos E Speck-Martins, Daniel Rocha Carvalho, Luciano Farage and 23 more

Open access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
8.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 116 citations in OpenAlex.

  1. Article
  2. Temporal loss ofGenes & development · 2026
    Article
  3. Article
  4. Review
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  8. Interpretation of RNA Universe and Coding Potential Using IntRNA.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  9. Review
  10. Article
  11. Review
  12. Article
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  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Neurodevelopmental Disorder Caused by Deletion ofThe New England journal of medicine · 2024
    Article
  20. TheProceedings of the National Academy of Sciences of the United States of America · 2024
    Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors at 13 institutions in 5 countries.

Lila AllouRG Development & Disease, Max Planck Institute for Molecular Genetics, Berlin, Germany.
Sara BalzanoMedical Genetics Unit, Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.
Andreas MaggRG Development & Disease, Max Planck Institute for Molecular Genetics, Berlin, Germany.ORCID http://orcid.org/0000-0003-4032-0175
Mathieu QuinodozMedical Genetics Unit, Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.
Beryl Royer-BertrandDivision of Genetic Medicine, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland.
Robert SchöpflinRG Development & Disease, Max Planck Institute for Molecular Genetics, Berlin, Germany.
Wing-Lee ChanInstitute for Medical and Human Genetics, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Carlos E Speck-MartinsGenetic Unit, SARAH Network of Rehabilitation Hospitals, Brasilia, Brazil.
Daniel Rocha CarvalhoGenetic Unit, SARAH Network of Rehabilitation Hospitals, Brasilia, Brazil.
Luciano FarageInstituto de Cardiologia do Distrito Federal, Brasilia, Brazil.ORCID http://orcid.org/0000-0002-2293-3771
Charles Marques LourençoFaculdade de Medicina, Centro Universitario Estácio, Ribeirão Preto, Brazil.ORCID http://orcid.org/0000-0002-2296-6098
Regina AlbuquerqueFaculdade Estadual de Medicina de São José do Rio Preto (FAMERP), São José do Rio Preto, Brazil.
Srilakshmi RajagopalDepartment of Medical Genetics, Tamil Nadu Dr M.G.R. Medical University, Chennai, India.
Sheela NampoothiriDepartment of Pediatric Genetics, Amrita Institute of Medical Sciences & Research Centre, Cochin, India.ORCID http://orcid.org/0000-0002-9575-0722
Belinda Campos-XavierDivision of Genetic Medicine, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland.
Carole ChiesaDivision of Genetic Medicine, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland.
Florence Niel-BütschiDivision of Genetic Medicine, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland.
Lars WittlerDepartment of Developmental Genetics, Max Planck Institute for Molecular Genetics, Berlin, Germany.
Bernd TimmermannSequencing Core Facility, Max Planck Institute for Molecular Genetics, Berlin, Germany.
Malte SpielmannRG Development & Disease, Max Planck Institute for Molecular Genetics, Berlin, Germany.
Michael I RobsonRG Development & Disease, Max Planck Institute for Molecular Genetics, Berlin, Germany.ORCID http://orcid.org/0000-0003-1126-3538
Alessa RingelRG Development & Disease, Max Planck Institute for Molecular Genetics, Berlin, Germany.
Verena HeinrichDepartment of Computational Molecular Biology, Max Planck Institute for Molecular Genetics, Berlin, Germany.
Giulia CovaRG Development & Disease, Max Planck Institute for Molecular Genetics, Berlin, Germany.
Guillaume AndreyRG Development & Disease, Max Planck Institute for Molecular Genetics, Berlin, Germany.ORCID http://orcid.org/0000-0002-0911-4907
Cesar A Prada-MedinaRG Development & Disease, Max Planck Institute for Molecular Genetics, Berlin, Germany.
Rosanna Pescini-GobertMedical Genetics Unit, Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0002-2434-7530
Sheila UngerDivision of Genetic Medicine, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland.
Luisa BonaféDivision of Genetic Medicine, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland.
Phillip GroteInstitute of Cardiovascular Regeneration, Center for Molecular Medicine, Goethe University, Frankfurt am Main, Germany.ORCID http://orcid.org/0000-0002-9254-1458
Carlo RivoltaMedical Genetics Unit, Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0002-0733-9950
Stefan MundlosRG Development & Disease, Max Planck Institute for Molecular Genetics, Berlin, Germany. mundlos@molgen.mpg.de.ORCID http://orcid.org/0000-0002-9788-3166
Andrea Superti-FurgaDivision of Genetic Medicine, Lausanne University Hospital (CHUV) and University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0002-3543-7531
Max Planck Institute for Molecular Genetics · DEUniversity of Lausanne · CHSarah Network of Rehabilitation Hospitals · BRAmrita Institute of Medical Sciences and Research Centre · INBerlin-Brandenburger Centrum für Regenerative Therapien · DECharité - Universitätsmedizin Berlin · DEFaculdade de Medicina de São José do Rio Preto · BRGoethe University Frankfurt · DEInstituto de Cardiologia do Distrito Federal · BRTamil Nadu Dr. M.G.R. Medical University · INUniversity of Basel · CHUniversity of Geneva · CHUniversity of Leicester · GB

Funding

Wellcome Trust 206475/Z/17/Z
6 · The paper itself

Abstract

Long non-coding RNAs (lncRNAs) can be important components in gene-regulatory networks

Indexed as

ExtremitiesTranscription, GeneticAnimalsCell LineChromatinDisease Models, AnimalFemaleHomeodomain ProteinsHumansLimb Deformities, CongenitalMiceMice, TransgenicRNA, Long NoncodingSequence DeletionTranscriptional ActivationChromatinEN1 protein, humanHomeodomain ProteinsRNA, Long Noncoding

Identifiers

PMID33568816
OpenAlexW3128829971

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.