Evidence map›Paper›PMID 33568716›Full record

ArticleScientific reports2021

Optimal control of the COVID-19 pandemic: controlled sanitary deconfinement in Portugal.

Cristiana J Silva, Carla Cruz, Delfim F M Torres, Alberto P Muñuzuri, Alejandro Carballosa, Iván Area, Juan J Nieto, Rui Fonseca-Pinto, Rui Passadouro, Estevão Soares Dos Santos and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. A Fokker-Planck framework for control of epidemics.Journal of mathematical biology · 2026
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  9. Fertility Does not Quarantine: Coronavirus Disease 2019 Pandemic Impacts on in Vitro Fertilization Clinical Pregnancy Rates.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2023
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Cristiana J SilvaDepartment of Mathematics, Center for Research and Development in Mathematics and Applications (CIDMA), University of Aveiro, 3810-193, Aveiro, Portugal. cjoaosilva@ua.pt.ORCID 0000-0002-7238-546X
Carla CruzDepartment of Mathematics, Center for Research and Development in Mathematics and Applications (CIDMA), University of Aveiro, 3810-193, Aveiro, Portugal.ORCID 0000-0003-4082-7523
Delfim F M TorresDepartment of Mathematics, Center for Research and Development in Mathematics and Applications (CIDMA), University of Aveiro, 3810-193, Aveiro, Portugal.ORCID 0000-0001-8641-2505
Alberto P MuñuzuriDepartment of Physics, Institute CRETUS, Group of Nonlinear Physics, Universidade de Santiago de Compostela, 15782, Santiago de Compostela, Spain.ORCID 0000-0002-0579-9347
Alejandro CarballosaDepartment of Physics, Institute CRETUS, Group of Nonlinear Physics, Universidade de Santiago de Compostela, 15782, Santiago de Compostela, Spain.ORCID 0000-0002-0858-8545
Iván AreaDepartamento de Matemática Aplicada II, E. E. Aeronáutica e do Espazo, Campus de Ourense, Universidade de Vigo, 32004, Ourense, Spain.ORCID 0000-0003-0872-5017
Juan J NietoInstituto de Matemáticas, Universidade de Santiago de Compostela, 15782, Santiago de Compostela, Spain.ORCID 0000-0001-8202-6578
Rui Fonseca-PintoCenter for Innovative Care and Health Technology (ciTechCare), Polytechnic of Leiria, Leiria, Portugal.ORCID 0000-0001-6774-5363
Rui PassadouroCenter for Innovative Care and Health Technology (ciTechCare), Polytechnic of Leiria, Leiria, Portugal.ORCID 0000-0002-7766-576X
Estevão Soares Dos SantosACES Pinhal Litoral-ARS Centro, Leiria, Portugal.ORCID 0000-0001-6567-1487
Wilson AbreuSchool of Nursing and Research Centre "Centre for Health Technology and Services Research/ESEP-CINTESIS", Porto, Portugal.ORCID 0000-0002-0847-824X
Jorge MiraDepartamento de Física Aplicada, Universidade de Santiago de Compostela, 15782, Santiago de Compostela, Spain. jorge.mira@usc.es.ORCID 0000-0002-6024-6294

Funding

Fundação para a Ciência e a Tecnologia Project Nr. 147 - RESEARCH4-COVID-19Instituto de Salud Carlos III COV20/00617Ministerio de Ciencia e Innovación of Spain COV20/00617Xunta de Galicia 2018-PG082Xunta de Galicia,Spain CRETUS Strategic Partnership (AGRUP2015/02)
6 · The paper itself

Abstract

The COVID-19 pandemic has forced policy makers to decree urgent confinements to stop a rapid and massive contagion. However, after that stage, societies are being forced to find an equilibrium between the need to reduce contagion rates and the need to reopen their economies. The experience hitherto lived has provided data on the evolution of the pandemic, in particular the population dynamics as a result of the public health measures enacted. This allows the formulation of forecasting mathematical models to anticipate the consequences of political decisions. Here we propose a model to do so and apply it to the case of Portugal. With a mathematical deterministic model, described by a system of ordinary differential equations, we fit the real evolution of COVID-19 in this country. After identification of the population readiness to follow social restrictions, by analyzing the social media, we incorporate this effect in a version of the model that allow us to check different scenarios. This is realized by considering a Monte Carlo discrete version of the previous model coupled via a complex network. Then, we apply optimal control theory to maximize the number of people returning to "normal life" and minimizing the number of active infected individuals with minimal economical costs while warranting a low level of hospitalizations. This work allows testing various scenarios of pandemic management (closure of sectors of the economy, partial/total compliance with protection measures by citizens, number of beds in intensive care units, etc.), ensuring the responsiveness of the health system, thus being a public health decision support tool.

Indexed as

Communicable Disease ControlModels, TheoreticalCOVID-19ForecastingHumansMonte Carlo MethodPandemicsPortugal

Identifiers

PMID33568716
PMCPMC7876047

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.