ArticleProceedings of the National Academy of Sciences of the United States of America2021
Selective modulation of interhemispheric connectivity by transcranial alternating current stimulation influences binaural integration.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 55 citations in OpenAlex.
- Effects of 40 Hz Brain Stimulation Across Modalities: A Comparative Narrative Review.Brain sciences · 2026Review
- Manipulating speech perception with amplitude-modulated kilohertz magnetic perturbation (AM-kTMP).bioRxiv : the preprint server for biology · 2026Article
- Enhanced intraparietal phase-lag synchronization in the high-gamma band during retention of visuospatial working memory.Biomedical engineering letters · 2026Article
- Cutaneous Alternating Current Stimulation Can Cause a Phasic Modulation of Speech Perception.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Variable E-field properties of dual-site tACS with phase lags.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- Neural changes to transcranial alternating current stimulation in the gamma range over the left frontoparietal network: A preliminary eLORETA EEG study.AIMS neuroscience · 2026Article
- Sensory stimuli dominate over rhythmic electrical stimulation in modulating behavior.PLoS biology · 2025Article
- Phase-lagged tACS between executive and default mode networks modulates working memory.Scientific reports · 2025Article
- Individual alpha frequency tACS reduces static functional connectivity across the default mode network.Frontiers in human neuroscience · 2025Article
- Article
- A bibliometric analysis of transcranial alternating current stimulation.Frontiers in neuroscience · 2024Article
- Top-down modulation of dichotic listening affects interhemispheric connectivity: an electroencephalography study.Frontiers in neuroscience · 2024Article
- Duplex perception reveals brainstem auditory representations are modulated by listeners' ongoing percept for speech.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Transcranial alternating current stimulation over multiple brain areas with non-zero phase delays other than 180 degrees modulates visuospatial working memory performance.Scientific reports · 2023Article
- Duplex perception reveals brainstem auditory representations are modulated by listeners' ongoing percept for speech.bioRxiv : the preprint server for biology · 2023Article
- Neurocognitive, physiological, and biophysical effects of transcranial alternating current stimulation.Trends in cognitive sciences · 2023Review
- Neurophysiological mechanisms of transcranial alternating current stimulation.Frontiers in neuroscience · 2023Review
- The Predictive Value of Individual Electric Field Modeling for Transcranial Alternating Current Stimulation Induced Brain Modulation.Frontiers in cellular neuroscience · 2022Article
- Evaluating interhemispheric connectivity during midline object recognition using EEG.PloS one · 2022Article
- The functional characterization of callosal connections.Progress in neurobiology · 2022Review
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brain connectivity plays a major role in the encoding, transfer, and integration of sensory information. Interregional synchronization of neural oscillations in the γ-frequency band has been suggested as a key mechanism underlying perceptual integration. In a recent study, we found evidence for this hypothesis showing that the modulation of interhemispheric oscillatory synchrony by means of bihemispheric high-density transcranial alternating current stimulation (HD-TACS) affects binaural integration of dichotic acoustic features. Here, we aimed to establish a direct link between oscillatory synchrony, effective brain connectivity, and binaural integration. We experimentally manipulated oscillatory synchrony (using bihemispheric γ-TACS with different interhemispheric phase lags) and assessed the effect on effective brain connectivity and binaural integration (as measured with functional MRI and a dichotic listening task, respectively). We found that TACS reduced intrahemispheric connectivity within the auditory cortices and antiphase (interhemispheric phase lag 180°) TACS modulated connectivity between the two auditory cortices. Importantly, the changes in intra- and interhemispheric connectivity induced by TACS were correlated with changes in perceptual integration. Our results indicate that γ-band synchronization between the two auditory cortices plays a functional role in binaural integration, supporting the proposed role of interregional oscillatory synchrony in perceptual integration.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.