Evidence map›Paper›PMID 33568463›Full record

ArticleJournal of clinical microbiology2021

On the Consequences of Poorly Defined Breakpoints for Rifampin Susceptibility Testing of Mycobacterium tuberculosis Complex.

Claudio U Köser, Sophia B Georghiou, Thomas Schön, Max Salfinger

Abstract readComment
In one paragraph

Article in Journal of clinical microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. All parts of the WHOMicrobiology spectrum · 2025
    Article
  6. Article
  7. First detection of aEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024
    Article
  8. Article
  9. Rifampicin has no role in treatment ofThe European respiratory journal · 2024
    Article
  10. Refined understanding of the impact of theMicrobiology spectrum · 2024
    Article
  11. Article
  12. Review
  13. Article
  14. Novel and reported compensatory mutations inFrontiers in microbiology · 2023
    Article
  15. Consequences ofAfrican journal of laboratory medicine · 2023
    Article
  16. Article
  17. Article
  18. Need for caution when interpreting XpertThe international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Claudio U KöserDepartment of Genetics, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0002-0232-846X
Sophia B GeorghiouFIND, Geneva, Switzerland.
Thomas SchönDepartment of Infectious Diseases, Kalmar County Hospital, Linköping University, Kalmar, Sweden.
Max SalfingerUniversity of South Florida College of Public Health and Morsani College of Medicine, Tampa, Florida, USA max@usf.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In a recent report of a systematic review of critical concentrations (CCs), the World Health Organization (WHO) lowered the rifampin (RIF) CC for antimicrobial susceptibility testing (AST) of the

Indexed as

Mycobacterium tuberculosisRifampinAntitubercular AgentsCulture MediaHumansMicrobial Sensitivity TestsAntitubercular AgentsCulture MediaRifampin

Identifiers

PMID33568463
PMCPMC8092724

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.