Evidence map›Paper›PMID 33568462›Full record

ArticleJournal of clinical microbiology2021

Deciphering an Adenovirus F41 Outbreak in Pediatric Hematopoietic Stem Cell Transplant Recipients by Whole-Genome Sequencing.

Caroline Lefeuvre, Maud Salmona, Linda Feghoul, Noémie Ranger, Séverine Mercier-Delarue, Laure Nizery, Aurélia Alimi, Jean-Hugues Dalle, Jérôme LeGoff

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

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  4. Circulation of adenovirus and other viruses in urban drainage channels: an environmental surveillance in Belém, Amazon region, Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Caroline LefeuvreDépartement des Agents Infectieux, Virologie et Greffes, AP-HP, Hôpital Saint-Louis, Paris, France.
Maud SalmonaDépartement des Agents Infectieux, Virologie et Greffes, AP-HP, Hôpital Saint-Louis, Paris, France.
Linda FeghoulDépartement des Agents Infectieux, Virologie et Greffes, AP-HP, Hôpital Saint-Louis, Paris, France.
Noémie RangerDépartement des Agents Infectieux, Virologie et Greffes, AP-HP, Hôpital Saint-Louis, Paris, France.
Séverine Mercier-DelarueDépartement des Agents Infectieux, Virologie et Greffes, AP-HP, Hôpital Saint-Louis, Paris, France.
Laure NizeryHématologie clinique, Hôpital Robert-Debré, GHU AP-HP Nord Université de Paris, Paris, France.
Aurélia AlimiHématologie clinique, Hôpital Robert-Debré, GHU AP-HP Nord Université de Paris, Paris, France.
Jean-Hugues DalleUniversité de Paris, Equipe INSIGHT, Inserm U976, Paris, France.
Jérôme LeGoffDépartement des Agents Infectieux, Virologie et Greffes, AP-HP, Hôpital Saint-Louis, Paris, France jerome.le-goff@aphp.fr.
Hôpital Saint-Louis · FRUniversité Paris Cité · FRAssistance Publique – Hôpitaux de Paris · FRHôpital Robert-Debré · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human adenovirus (HAdV) represents a major cause of mortality and morbidity in pediatric recipients of allogeneic hematopoietic stem cell transplants (HSCT). HAdV species F type 41 (HAdV-F41) infections in HSCT patients are scarce, whereas HAdV-F41 circulates commonly in healthy individuals. Between March and July 2018, HAdV-F41 infections were identified in four children (A, B, C, and E) who received allogeneic HSCT and one child before HSCT (D) at Robert Debré Hospital, Paris, France. We report here the clinical course of HAdV-F41 infection and the phylogenetic investigation to identify interpatient transmission. HAdV DNA was quantified in stool and plasma samples by real-time PCR. HAdV type was determined by sequencing of the fiber and hexon genes. Phylogenetic investigation was done with whole-genome sequences obtained by next-generation sequencing. HAdV loads in stool samples ranged from 6.60 to 10.10 log

Indexed as

Adenoviruses, HumanAdenovirus Infections, HumanHematopoietic Stem Cell TransplantationAdenoviridaeChildDisease OutbreaksFranceHumansParisPhylogenyadenovirusadenovirus diseasehematopoietic stem cell transplantationnext-generation sequencingoutbreakphylogenyplasmastoolsWGSwhole genome

Identifiers

PMID33568462
PMCPMC8091842
OpenAlexW3127606017

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.