Evidence map›Paper›PMID 33568455›Full record

ArticlemSphere2021

APEX2 Proximity Proteomics Resolves Flagellum Subdomains and Identifies Flagellum Tip-Specific Proteins in Trypanosoma brucei.

Daniel E Vélez-Ramírez, Michelle M Shimogawa, Sunayan S Ray, Andrew Lopez, Shima Rayatpisheh, Gerasimos Langousis, Marcus Gallagher-Jones, Samuel Dean, James A Wohlschlegel, Kent L Hill

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSphere, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. FAP20 is required for flagellum assembly inMolecular biology of the cell · 2024
    Article
  3. Article
  4. FAP20 is required for flagellum assembly inbioRxiv : the preprint server for biology · 2024
    Article
  5. Identification of Protein Partners by APEX2 Proximity Labeling.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Gene editing of putative cAMP and CaThe Journal of eukaryotic microbiology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Daniel E Vélez-RamírezDepartment of Microbiology, Immunology, and Molecular Genetics, University of California Los Angeles, Los Angeles, California, USA.ORCID 0000-0002-7687-0120
Michelle M ShimogawaDepartment of Microbiology, Immunology, and Molecular Genetics, University of California Los Angeles, Los Angeles, California, USA.
Sunayan S RayDepartment of Microbiology, Immunology, and Molecular Genetics, University of California Los Angeles, Los Angeles, California, USA.ORCID 0000-0003-4260-8092
Andrew LopezDepartment of Microbiology, Immunology, and Molecular Genetics, University of California Los Angeles, Los Angeles, California, USA.
Shima RayatpishehDepartment of Biological Chemistry, University of California Los Angeles, Los Angeles, California, USA.
Gerasimos LangousisDepartment of Microbiology, Immunology, and Molecular Genetics, University of California Los Angeles, Los Angeles, California, USA.
Marcus Gallagher-JonesDepartment of Chemistry and Biochemistry, UCLA-DOE Institute for Genomics and Proteomics, Los Angeles, California, USA.
Samuel DeanWarwick Medical School, University of Warwick, Coventry, United Kingdom.
James A WohlschlegelDepartment of Biological Chemistry, University of California Los Angeles, Los Angeles, California, USA.
Kent L HillDepartment of Microbiology, Immunology, and Molecular Genetics, University of California Los Angeles, Los Angeles, California, USA kenthill@microbio.ucla.edu.ORCID 0000-0001-6529-1273
University of California, Los Angeles · USCalifornia NanoSystems Institute · USUniversity of Warwick · GB

Funding

Biochemical and Functional Analysis of TrypaninR01AI052348 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HILL, KENT L · 2002 to 2023
$7.4M
Proteolytic Control of Iron Metabolism by the Ubiquitin Ligase FBXL5R01GM089778 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WOHLSCHLEGEL, JAMES AKIRA · 2010 to 2023
$4.0M
Biochemical and Functional Analysis of TrypaninR56AI052348 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HILL, KENT L · 2007 to 2007
$374k
Social Motility and cAMP signaling in chemotaxis and parasite-vector interactions of African trypanosomesR21AI142544 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HILL, KENT L · 2019 to 2020
$187k
NIAID NIH HHS R01 AI052348NIAID NIH HHS R21 AI142544NIAID NIH HHS R56 AI052348NIGMS NIH HHS R01 GM089778Wellcome TrustWellcome Trust 104627/Z/14/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ProteomicsDNA-(Apurinic or Apyrimidinic Site) LyaseEndonucleasesFlagellaHumansMultifunctional EnzymesProteomeProtozoan ProteinsSignal TransductionTrypanosoma brucei bruceiAPEX2 protein, humanDNA-(Apurinic or Apyrimidinic Site) LyaseEndonucleasesMultifunctional EnzymesProteomeProtozoan Proteinscell signalingflagellaTrypanosoma

Identifiers

PMID33568455
PMCPMC8141408
OpenAlexW3126837652

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.