Evidence map›Paper›PMID 33568371›Full record

Observational studyBMJ open2021

What are the barriers to the completion of a home-based rehabilitation programme for patients awaiting surgery for lung cancer: a prospective observational study.

Heloise Catho, Sebastien Guigard, Anne-Claire Toffart, Gil Frey, Thibaut Chollier, Pierre-Yves Brichon, Jean-François Roux, Linda Sakhri, Dominique Bertrand, Charles Aguirre and 4 more

2 registry-linked trialsAbstract readObservational Study
In one paragraph

Observational study in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03530059 completednot on this map

Feasibility at Home of a Rehabilitation Program Before Thoracic Surgery, for Pulmonary Parenchyma Exeresis

TypeobservationalSponsorUniversity Hospital, GrenobleRan2018 to 2019Enrolled50ConditionsRespiratory Disease, Thoracic Surgery, Lung CancerArmsHome-based rehabilitation
NCT07434947 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Study of Three Endpoints to Assess the Benefit of Rehabilitation in Patients With Advanced Non-small Cell Lung Cancer Controlled After at Least 6 Months of Systemic Treatment

TypeobservationalSponsorUniversity Hospital, GrenobleRan2026 to 2027Enrolled63ConditionsLung Cancer (NSCLC)
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Heloise CathoDepartment of Pneumology, University Hospital of Grenoble, Grenoble, France.
Sebastien GuigardDepartment of Thoracic surgery, Clinique Belledonne, Grenoble, France.
Anne-Claire ToffartDepartment of Pneumo-oncology, University Hospital of Grenoble, Grenoble, France.
Gil FreyDepartment of Thoracic surgery, University Hospital of Grenoble, Grenoble, France.
Thibaut ChollierDepartment of Thoracic surgery, University Hospital of Grenoble, Grenoble, France.
Pierre-Yves BrichonDepartment of Thoracic surgery, University Hospital of Grenoble, Grenoble, France.
Jean-François RouxDepartment of Thoracic surgery, Clinique des Cèdres, Grenoble, France.
Linda SakhriDepartment of Oncology, Institut Daniel Hollard, groupe hospitalier mutualiste, Grenoble, France.
Dominique BertrandPneumology, Pulmonary and Sleep Clinic, Saint Ismier, France.
Charles AguirrePhysiotherapy, center Pol'air, Grenoble, France.
Sandy GorainResearch and Development, Agir à Dom, Association, Meylan, France.
Bernard WuyamClinical Research, HP2, INSERM U1042, Université Grenoble Alpes, Grenoble, France.
François ArbibDepartment of Pneumology, University Hospital of Grenoble, Grenoble, France.
Jean Christian BorelResearch and Development, Agir à Dom, Association, Meylan, France j.borel@agiradom.com.ORCID 0000-0003-4140-6210

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesHome-based rehabilitation programmes (H-RPs) could facilitate the implementation of pulmonary rehabilitation prior to resection for non-small cell lung cancer (NSCLC), but their feasibility has not been evaluated. The aim of this study was to identify determinants of non-completion of an H-RP and the factors associated with medical events occurring 30 days after hospital discharge.

designA prospective observational study.

interventionAll patients with confirmed or suspected NSCLC were enrolled in a four-component H-RP prior to surgery: (i) smoking cessation, (ii) nutritional support, (iii) physiotherapy (at least one session/week) and (iv) home cycle-ergometry (at least three times/week). OUTCOMES: The H-RP was defined as 'completed' if the four components were performed before surgery.

resultsOut of 50 patients included, 42 underwent surgery (80% men; median age: 69 (IQR 25%-75%; 60-74) years; 64% Chronic Obstructive Pulmonary Disease (COPD); 29% type 2 diabetes). Twenty patients (48%) completed 100% of the programme. The median (IQR) duration of the H-RP was 32 (19; 46) days. Multivariate analysis showed polypharmacy (n=24) OR=12.2 (95% CI 2.0 to 74.2), living alone (n=8) (single vs couple) OR=21.5 (95% CI 1.4 to >100) and a long delay before starting the H-RP (n=18) OR=6.24 (95% CI 1.1 to 36.6) were independently associated with a risk of non-completion. In univariate analyses, factors associated with medical events at 30 days were H-RP non-completion, diabetes, polypharmacy, social precariousness and female sex.

conclusionFacing multiple comorbidities, living alone and a long delay before starting the rehabilitation increase the risk of not completing preoperative H-RP. TRIAL REGISTRATION NUMBER: NCT03530059.

Indexed as

Carcinoma, Non-Small-Cell LungDiabetes Mellitus, Type 2Lung NeoplasmsPulmonary Disease, Chronic ObstructiveAgedFemaleHumansMaleProspective Studiesrehabilitation medicinerespiratory tract tumoursthoracic surgery

Identifiers

PMID33568371
PMCPMC7878140

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.