Evidence map›Paper›PMID 33567772›Full record

ArticleBiomedicines2021

Oral Administration of Probiotic

Toshiaki Ishii, Hidefumi Furuoka, Motohiro Kaya, Tetsuya Kuhara

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Nutrients · 2025
    Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Oral Administration of ProbioticInternational journal of molecular sciences · 2024
    Article
  14. Brain sciences · 2024
    Article
  15. Review
  16. Review
  17. Review
  18. Neuroprotective Effects ofInternational journal of molecular sciences · 2023
    Article
  19. Nutrients · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Toshiaki IshiiDepartment of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080-8555, Hokkaido, Japan.ORCID 0000-0002-6431-3263
Hidefumi FuruokaDepartment of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080-8555, Hokkaido, Japan.
Motohiro KayaCenter for Regional Collaboration in Research and Education, Obihiro University of Agriculture and Veterinary Medicine, Obihiro 080-8555, Hokkaido, Japan.
Tetsuya KuharaNext Generation Science Institute Morinaga Milk Industry Co., Ltd., Zama 252-8583, Kanagawa, Japan.
Obihiro University of Agriculture and Veterinary Medicine · JPMorinaga (Japan) · JP

Funding

a Grant-in-Aid for Scientific Research (C) from the Japan Society for the Promotion of Science [20K06425]research grants from Morinaga Milk Industry Co., Ltd. [J20011]
6 · The paper itself

Abstract

We previously reported that 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease (PD) model mice (PD mice) facilitate hippocampal memory extinction, which may be the cause of cognitive impairment in PD. Recent studies on the consumption of probiotics have reported a variety of beneficial effects on the central nervous system via the microbiota-gut-brain axis. In this study, we investigated the effects of oral administration of

Indexed as

Bifidobacterium breve strain A1 [MCC1274] (B. breve A1)dopaminehippocampusmemory extinctionMPTPneuropsinParkinson’s diseasepostsynaptic density protein-95 (PSD95)spinesubstantia nigra pars compacta (SNpc)synaptophysin (SYP)

Identifiers

PMID33567772
PMCPMC7914481
OpenAlexW3126476607

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.