Evidence map›Paper›PMID 33567740›Full record

ArticleMolecules (Basel, Switzerland)2021

Synthesis of Four Pentacyclic Triterpene-Sialylglycopeptide Conjugates and Their Affinity Assays with Hemagglutinin.

Mei Luo, Ximin Wu, Yiming Li, Fujiang Guo

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mei LuoSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Ximin WuSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Yiming LiSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Fujiang GuoSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.ORCID 0000-0003-4073-4773
Shanghai University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Influenza outbreaks pose a serious threat to human health. Hemagglutinin (HA) is an important target for influenza virus entry inhibitors. In this study, we synthesized four pentacyclic triterpene conjugates with a sialylglycopeptide scaffold through the Cu(I)-catalyzed alkyne-azide cycloaddition reaction (CuAAC) and prepared affinity assays of these conjugates with two HAs, namely H1N1 (A/WSN/1933) and H5N1 (A/Hong Kong/483/97), respectively. With a dissociation constant (

Indexed as

Chemistry Techniques, SyntheticGlycopeptidesHemagglutininsSurface Plasmon ResonanceTriterpenesGlycopeptidesHemagglutininsTriterpeneshemagglutinininfluenza viruspentacyclic triterpenessialylglycopeptide

Identifiers

PMID33567740
PMCPMC7915185
OpenAlexW3128097932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.