ArticleAntibiotics (Basel, Switzerland)2021
In-Water Antibiotic Dosing Practices on Pig Farms.
Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Pharmacokinetic-Pharmacodynamic Cutoff Values for Doxycycline in Pigs to Support the Establishment of Clinical Breakpoints for Antimicrobial Susceptibility Testing.Journal of veterinary pharmacology and therapeutics · 2025Pooled it
- Water line biofilm regrowth dynamics in six wean-to-finish farms post peracetic acid water line cleaning and disinfection.Scientific reports · 2026Article
- Presence of antimicrobial resistance genes in biofilms from swine drinking water pipes before and after treatment with peracetic acid.Frontiers in microbiology · 2026Article
- A high content (30%) stable doxycycline hyclate drinking-water solution for broilers: preparation, stability, and bioequivalence.Frontiers in veterinary science · 2025Article
- Effect of single parenteral administration of marbofloxacin on bacterial load and selection of resistant Enterobacteriaceae in the fecal microbiota of healthy pigs.BMC veterinary research · 2024Article
- Delivery strategies to improve piglets exposure to oral antimicrobials.BMC veterinary research · 2024Article
- Article
- An economic assessment of alternative antimicrobial use scenarios on pig farms.Frontiers in veterinary science · 2024Article
- Qualitative risk assessment of homogeneity, stability, and residual concentrations of antimicrobials in medicated feed and drinking water in pig rearing.BMC veterinary research · 2023Article
- Optimization of Veterinary Antimicrobial Treatment in Companion and Food Animals.Antibiotics (Basel, Switzerland) · 2022Article
- Antimicrobial stewardship in Australia: the role of qualitative research in programme development.JAC-antimicrobial resistance · 2021Review
- Water Distribution Systems in Pig Farm Buildings: Critical Elements of Design and Management.Animals : an open access journal from MDPI · 2021Article
- What Matters in Piglets' Exposure to Antibiotics Administered through Drinking Water?Antibiotics (Basel, Switzerland) · 2021Article
- Effect of Drinking Water Distribution System Design on Antimicrobial Delivery to Pigs.Animals : an open access journal from MDPI · 2021Article
- Exploring Farmers' Reasons for Antibiotic Use and Misuse in Pig Farms in Brazil.Antibiotics (Basel, Switzerland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pigs reared on many farms are mass-medicated for short periods with antibiotics through their drinking water to control bacterial pathogen loads and, if a disease outbreak occurs, to treat pigs until clinical signs are eliminated. Farm managers are responsible for conducting in-water antibiotic dosing events, but little is known about their dosing practices. We surveyed managers of 25 medium to large single-site and multi-site pig farming enterprises across eastern and southern Australia, using a mixed methods approach (online questionnaire followed by a one-on-one semi-structured interview). We found wide variation in the antibiotics administered, the choice and use of dosing equipment, the methods for performing dosing calculations and preparing antibiotic stock solutions, the commencement time and duration of each daily dosing event, and the frequency of administration of metaphylaxis. Farm managers lacked data on pigs' daily water usage patterns and wastage and the understanding of pharmacology and population pharmacometrics necessary to optimize in-water dosing calculations and regimens and control major sources of between-animal variability in systemic exposure of pigs to antibiotics. There is considerable scope to increase the effectiveness of in-water dosing and reduce antibiotic use (and cost) on pig farms by providing farm managers with measurement systems, technical guidelines, and training programs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.