Evidence map›Paper›PMID 33567548›Full record

ArticleJournal of clinical medicine2021

Leukocyte Immunoglobulin-Like Receptor A3 (LILRA3): A Novel Marker for Lymphoma Development among Patients with Young Onset Sjogren's Syndrome.

Evangelia Argyriou, Adrianos Nezos, Petros Roussos, Aliki Venetsanopoulou, Michael Voulgarelis, Kyriaki Boki, Athanasios G Tzioufas, Haralampos M Moutsopoulos, Clio P Mavragani

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Sjogren's Syndrome: Recent Updates.Journal of clinical medicine · 2022
    Article
  3. Sjögren syndrome: looking forward to the future.Therapeutic advances in musculoskeletal disease · 2022
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Evangelia ArgyriouDepartment of Physiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0002-8099-8872
Adrianos NezosDepartment of Physiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Petros RoussosDepartment of Physiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Aliki VenetsanopoulouDepartment of Pathophysiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0003-4280-9193
Michael VoulgarelisDepartment of Pathophysiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Kyriaki BokiRheumatology Unit, Sismanogleio General Hospital, 15126 Athens, Greece.
Athanasios G TzioufasDepartment of Pathophysiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Haralampos M MoutsopoulosAthens Academy, Chair Medical Sciences/Immunology, 10679 Athens, Greece.
Clio P MavraganiDepartment of Physiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
National and Kapodistrian University of Athens · GRAcademy of Athens · GRSismanoglio General Hospital · GR

Funding

HarmonicSS 731944Hellenic Rheumatology Society -
6 · The paper itself

Abstract

backgroundPrimary Sjogren's syndrome (SS) is an autoimmune disease with a strong predilection for lymphoma development, with earlier disease onset being postulated as an independent risk factor for this complication. Variations of the

methodsStudy population, all of Greek origin, included 101 SS cases with a current or previous diagnosis of lymphoma (SS-lymphoma, SS-L) and 301 primary SS patients not complicated by lymphoma (SS-non-lymphoma, SS-nL). All SS patients fulfilled the 2016 SS American College of Rheumatology/European league against Rheumatism (ACR/EULAR) classification criteria. A total of 381 healthy controls (HC) of similar age/sex/race distribution were also included. On the basis of the age of SS onset and the presence or absence of adverse predictors for lymphoma development, SS patients were further stratified into younger (≤40 years) and older (>40 years) age of disease onset, as well as into high/medium and low risk groups. Polymerase chain reaction (PCR) was implemented for the detection of the following

resultsWhile no statistically significant differences were detected in the overall frequency of

conclusionThe functional

Indexed as

chronic inflammationgenesLILRA3lymphomaSjogren’s syndrome

Identifiers

PMID33567548
PMCPMC7915360
OpenAlexW3126702598

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.