Evidence map›Paper›PMID 33567545›Full record

ArticleJournal of clinical medicine2021

Perinatal Outcomes of Small for Gestational Age in Twin Pregnancies: Twin vs. Singleton Charts.

Veronica Giorgione, Corey Briffa, Carolina Di Fabrizio, Rohan Bhate, Asma Khalil

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Adverse neonatal outcomes in small-for-gestational age twins identified using twin vs singleton growth charts: systematic review and meta-analysis.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2025
    Pooled it
  2. Prognostic performance of umbilical artery Doppler-based classification in monochorionic pregnancies complicated by selective fetal growth restriction.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2026
    Article
  3. Article
  4. Article
  5. Accuracy of ultrasound estimation of fetal weight in twin pregnancy.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Article
  6. ISUOG Practice Guidelines (updated): role of ultrasound in twin pregnancy.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2025
    Article
  7. Article
  8. Article
  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Veronica GiorgioneTwins Trust Centre for Research and Clinical Excellence, St George's University Hospitals NHS Foundation Trust, Blackshaw Road, London SW17 0RE, UK.ORCID 0000-0003-3991-9308
Corey BriffaTwins Trust Centre for Research and Clinical Excellence, St George's University Hospitals NHS Foundation Trust, Blackshaw Road, London SW17 0RE, UK.ORCID 0000-0002-1508-3473
Carolina Di FabrizioTwins Trust Centre for Research and Clinical Excellence, St George's University Hospitals NHS Foundation Trust, Blackshaw Road, London SW17 0RE, UK.
Rohan BhateTwins Trust Centre for Research and Clinical Excellence, St George's University Hospitals NHS Foundation Trust, Blackshaw Road, London SW17 0RE, UK.ORCID 0000-0002-3024-4327
Asma KhalilTwins Trust Centre for Research and Clinical Excellence, St George's University Hospitals NHS Foundation Trust, Blackshaw Road, London SW17 0RE, UK.ORCID 0000-0003-2802-7670
St George's, University of London · GBSt George’s University Hospitals NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Twin pregnancies are commonly assessed using singleton growth and birth weight reference charts. This practice has led to a significant number of twins labelled as small for gestational age (SGA), causing unnecessary interventions and increased risk of iatrogenic preterm birth. However, the use of twin-specific charts remains controversial. This study aims to assess whether twin-specific estimated fetal weight (EFW) and birth weight (BW) charts are more predictive of adverse outcomes compared to singleton charts. Centiles of EFW and BW were calculated using previously published singleton and twin charts. Categorical data were compared using Chi-square or McNemar tests. The study included 1740 twin pregnancies, with the following perinatal adverse outcomes recorded: perinatal death, preterm birth <34 weeks, hypertensive disorders of pregnancy (HDP) and admissions to the neonatal unit (NNU). Twin-specific charts identified prenatally and postnatally a smaller proportion of infants as SGA compared to singleton charts. However, twin charts showed a higher percentage of adverse neonatal outcomes in SGA infants than singleton charts. For example, perinatal death (SGA 7.2% vs. appropriate for gestational age (AGA) 2%,

Indexed as

birth weightchorionicity-specificestimated fetal weightfetal growth restrictionreference chartssingletonsmall for gestational agetwin pregnancyultrasound

Identifiers

PMID33567545
PMCPMC7916041
OpenAlexW3127054650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.