ArticleLife (Basel, Switzerland)2021
F1099L-CFTR (c.3297C>G) has Impaired Channel Function and Associates with Mild Disease Phenotypes in Two Pediatric Patients.
Xiaoying Zhang, Jaspal S Hothi, Yanhui H Zhang, Aixia Ren, Michael J Rock, Saumini Srinivasan, Dennis C Stokes, Anjaparavanda P Naren, Weiqiang Zhang
Open access · goldAbstract read
In one paragraphArticle in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 0 citations in OpenAlex.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
9 authors at 3 institutions in 1 country.
Xiaoying ZhangDepartment of Pediatrics, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38103, USA.
Jaspal S HothiDepartment of Pediatrics, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38103, USA.
Yanhui H ZhangDepartment of Bioscience Research, College of Dentistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA.ORCID 0000-0001-8277-8008 Aixia RenDepartment of Pediatrics, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38103, USA.
Michael J RockDepartment of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA.
Saumini SrinivasanDepartment of Pediatrics, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38103, USA.
Dennis C StokesDepartment of Pediatrics, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38103, USA.
Anjaparavanda P NarenDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, R-4041, Cincinnati, OH 45229, USA.
Weiqiang ZhangDepartment of Pediatrics, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38103, USA.ORCID 0000-0002-7278-5033 University of Tennessee Health Science Center · USCincinnati Children's Hospital Medical Center · USUniversity of Wisconsin–Madison · US
Funding
Characterization of an inhibitory protein complex for cystic fibrosis therapyR01HL123535 · NHLBI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI ZHANG, WEIQIANG · 2014 to 2018
$1.9MInvestigating of the Mechanisms of Action of CFTR Correctors in RescuingDelta F508-CFTRR01HL147351 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI NAREN, ANJAPARAVANDA P · 2020 to 2023
$1.7MNHLBI NIH HHS R01 HL123535NHLBI NIH HHS R01 HL147351
6 · The paper itselfAbstract
(1) Background: many rare
Indexed as
CFTRCFTR modulatorscystic fibrosis (CF)F1099L-CFTRpersonalized medicineprotein channelVX-809 (lumacaftor)
Identifiers
PMID33567498
PMCPMC7915716
OpenAlexW3127207591
What OpenQuestion holds
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