Evidence map›Paper›PMID 33567487›Full record

ArticleCurrent oncology (Toronto, Ont.)2021

Cerebral Invasive Aspergillosis in a Case of Chronic Lymphocytic Leukemia with Bruton Tyrosine Kinase Inhibitor.

Omar Alkharabsheh, Alhareth Alsayed, Diana M Morlote, Amitkumar Mehta

Open access · goldAbstract readCase Reports
In one paragraph

Article in Current oncology (Toronto, Ont.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

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  10. Neurologic Complications of Cancer Therapies.Current neurology and neuroscience reports · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Omar AlkharabshehMitchell Cancer Institute, University of South Alabama, Mobile, AL 36604, USA.ORCID 0000-0002-5299-4233
Alhareth AlsayedMitchell Cancer Institute, University of South Alabama, Mobile, AL 36604, USA.
Diana M MorloteDepartment of Pathology, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
Amitkumar MehtaO'Neal Comprehensive Cancer Center at UAB, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
University of Alabama at Birmingham · USUSA Mitchell Cancer Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bruton tyrosine kinase (BTK) inhibitors have become an important therapy for untreated and previously treated patients with chronic lymphocytic leukemia (CLL). Despite improved outcomes, rare adverse events, such as invasive fungal infections, have been reported with the use of first-generation BTK inhibitors. Invasive fungal infections carry a high morbidity and mortality risk. There have been several case reports describing the association between aspergillosis and ibrutinib treatment, but none with acalabrutinib, to our knowledge. In this case report, we describe a patient with CLL who developed an intracranial

Indexed as

AspergillosisInvasive Fungal InfectionsLeukemia, Lymphocytic, Chronic, B-CellAgammaglobulinaemia Tyrosine KinaseHumansProtein Kinase InhibitorsAgammaglobulinaemia Tyrosine KinaseProtein Kinase InhibitorsacalabrutinibCLLinvasive aspergillosis

Identifiers

PMID33567487
PMCPMC7985758
OpenAlexW3128386210

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.