Evidence map›Paper›PMID 33566985›Full record

ArticleRevista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo2021

OCCURRENCE OF UNUSUAL HAEMOGLOBINOPATHIES IN BALOCHISTAN: HB SD AND HB SE - PRESENTATION WITH OSTEOMYELITIS.

Usman Tauseef, Misbah Anjum, Mohsina Ibrahim, Hina Sabih Baqai, Abubakar Tauseef, Marium Tauseef, Muhammad Sohaib Asghar, Maryam Zafar, Uzma Rasheed, Nimra Shaikh

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Usman TauseefNational Institute of Child Health, Karachi, Pakistan.ORCID http://orcid.org/0000-0002-9545-9505
Misbah AnjumNational Institute of Child Health, Karachi, Pakistan.ORCID http://orcid.org/0000-0002-9834-8632
Mohsina IbrahimNational Institute of Child Health, Karachi, Pakistan.ORCID http://orcid.org/0000-0002-7007-8896
Hina Sabih BaqaiNational Institute of Child Health, Karachi, Pakistan.ORCID http://orcid.org/0000-0001-9406-6390
Abubakar TauseefDow University of Health Sciences, Karachi, Pakistan.ORCID http://orcid.org/0000-0002-4317-1868
Marium TauseefJinnah Sindh Medical University, Karachi, Pakistan.ORCID http://orcid.org/0000-0002-9302-5324
Muhammad Sohaib AsgharDow University of Health Sciences, Karachi, Pakistan.ORCID http://orcid.org/0000-0001-6705-2030
Maryam ZafarDow University of Health Sciences, Karachi, Pakistan.ORCID http://orcid.org/0000-0003-2329-0082
Uzma RasheedLiaquat National Hospital and Medical College, Karachi, Pakistan.ORCID http://orcid.org/0000-0003-0596-7766
Nimra ShaikhLiaquat National Hospital and Medical College, Karachi, Pakistan.ORCID http://orcid.org/0000-0001-5515-7353
National Institute of Child Health · PKDow University of Health Sciences · PKLiaquat National Hospital · PKJinnah Sindh Medical University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe two cases of unusual variants of sickle cell disease. CASE DESCRIPTION: We present two cases of sickle cell disease variants (haemoglobinopathies), from unrelated families, in the state of Balochistan (Pakistan). One was diagnosed with sickle cell disease in the haemoglobin electrophoresis, whereas the other was diagnosed with sickle cell SE disease. Both were diagnosed based on the presentation of osteomyelitis. COMMENTS: Haemoglobin SD disease (Hb SD) and haemoglobin SE disease (Hb SE) are rare haemoglobinopathies in the world. The lack of available literature suggests that both are variants of sickle cell disease (SCD), with heterogeneous nature. The prevalence of sickle cell disease with compound heterozygotes was found at a variable frequency in the population of the Asian Southeast. The frequency of osteomyelitis in SCD is 12 to 18%, but its occurrence among variant haemoglobinopathies is little reported. Both reported cases presented with osteomyelitis as a characteristic of the disease presentation.

Indexed as

Administration, IntravenousAdministration, OralAnemia, Sickle CellAnti-Bacterial AgentsAntisickling AgentsBlood Protein ElectrophoresisChildFemaleHemoglobinopathiesHeterozygoteHumansHydroxyureaMagnetic Resonance ImagingMaleMass ScreeningOsteomyelitisAnti-Bacterial AgentsAntisickling AgentsHydroxyurea

Identifiers

PMID33566985
PMCPMC7870096
OpenAlexW3126494221

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.