Evidence map›Paper›PMID 33566306›Full record

ArticleClinical journal of gastroenterology2021

Immunohistochemical detection of procalcitonin in fibrolamellar hepatocellular carcinoma.

Kotaro Matsumoto, Kentaro Kikuchi, Ayako Hara, Hiromichi Tsunashima, Koichi Tsuneyama, Shinpei Doi

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Clinical journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kotaro MatsumotoDepartment of Gastroenterology, Teikyo University Mizonokuchi Hospital, Kawasaki, Japan. kotaro1122shonai@gmail.com.ORCID http://orcid.org/0000-0002-4239-3063
Kentaro KikuchiFourth Department of Internal Medicine, Teikyo University Mizonokuchi Hospital, Kawasaki, Japan.
Ayako HaraDepartment of Gastroenterology, Teikyo University Mizonokuchi Hospital, Kawasaki, Japan.
Hiromichi TsunashimaDepartment of Gastroenterology, Teikyo University Mizonokuchi Hospital, Kawasaki, Japan.
Koichi TsuneyamaDepartment of Pathology and Laboratory Medicine, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
Shinpei DoiDepartment of Gastroenterology, Teikyo University Mizonokuchi Hospital, Kawasaki, Japan.
Teikyo University · JPTokushima University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 25-year-old woman with fever and epigastric pain was referred to our hospital. Blood examination showed significant liver dysfunction, markedly high C-reactive protein (CRP 19.1 mg/dL) and procalcitonin (48.3 ng/mL) levels. Dynamic computed tomography showed a tumor approximately 120 mm in size in the right lobe of the liver, but with no abscess formation. The patient was hospitalized and started on antibiotics; her CRP level improved, but the procalcitonin level did not decrease. Histopathological examination of the liver tumor biopsy revealed fibrolamellar hepatocellular carcinoma (FLC). Positive staining of the FLC with an anti-procalcitonin antibody suggested the production of procalcitonin.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsAdultFemaleHumansProcalcitoninProcalcitoninFibrolamellar hepatocellular carcinomaImmunohistochemical examinationProcalcitonin

Identifiers

PMID33566306
PMCPMC8154767
OpenAlexW3128103137

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.