Evidence map›Paper›PMID 33566217›Full record

ArticleVirus genes2021

Giant virus-related sequences in the 5300-year-old Ötzi mummy metagenome.

Gabriel Augusto Pires de Souza, Clara Rolland, Bariaa Nafeh, Bernard La Scola, Philippe Colson

Abstract read
PubMed Publisher
In one paragraph

Article in Virus genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 4 countries.

Gabriel Augusto Pires de SouzaInstitut de Recherche Pour le Développement (IRD), Assistance Publique - Hôpitaux de Marseille (AP-HM), MEPHI, Aix-Marseille Univ., 27 boulevard Jean Moulin, 13005, Marseille, France.
Clara RollandInstitut de Recherche Pour le Développement (IRD), Assistance Publique - Hôpitaux de Marseille (AP-HM), MEPHI, Aix-Marseille Univ., 27 boulevard Jean Moulin, 13005, Marseille, France.
Bariaa NafehInstitut de Recherche Pour le Développement (IRD), Assistance Publique - Hôpitaux de Marseille (AP-HM), MEPHI, Aix-Marseille Univ., 27 boulevard Jean Moulin, 13005, Marseille, France.
Bernard La ScolaInstitut de Recherche Pour le Développement (IRD), Assistance Publique - Hôpitaux de Marseille (AP-HM), MEPHI, Aix-Marseille Univ., 27 boulevard Jean Moulin, 13005, Marseille, France.
Philippe ColsonInstitut de Recherche Pour le Développement (IRD), Assistance Publique - Hôpitaux de Marseille (AP-HM), MEPHI, Aix-Marseille Univ., 27 boulevard Jean Moulin, 13005, Marseille, France. philippe.colson@univ-amu.fr.ORCID http://orcid.org/0000-0001-6285-0308
Aix-Marseille Université · FRMéditerranée Infection Foundation · FRUniversidade Federal de Minas Gerais · BR

Funding

Agence Nationale de la Recherche Méditerranée-Infection 10-IAHU-03Région Provence Alpes Côte d'Azur and Europe FEDER PRIMMI
6 · The paper itself

Abstract

Giant viruses have brought new perspectives on the virosphere. They have been increasingly described in humans, including in several metagenomic studies. Here, we searched into the metagenome of the 5300-year-old Ötzi mummy for the presence of giant virus-related sequences using MG-Digger pipeline. We found 19 reads (0.00006% of the total read number) that best matched (mean ± standard deviation (range) for e-values of 5.0E-6 ± 1.4E-6 (6.0E-5-4.0E-10) and for amino acid identity of 69.9 ± 8.7% (46.4-84.9%) and most significantly with sequences from various giant viruses, including mostly mimiviruses. This expands current knowledge on the ubiquity and relationship with humans of giant viruses.

Indexed as

MetagenomeDatasets as TopicGiant VirusesHumansMummiesGiant virusMetagenomeMimivirusMummyOtzi

Identifiers

PMID33566217
OpenAlexW3126842457

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.