Evidence map›Paper›PMID 33566116›Full record

ReviewDer Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen2021

[Neoadjuvant and perioperative treatment of gastric cancer, current studies and new biomarkers].

G Stocker, R Thieme, F Lordick

Abstract readReview
PubMed Publisher
In one paragraph

Review in Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

G StockerKlinik für Onkologie, Gastroenterologie, Hepatologie, Pneumologie und Infektiologie, Universitätsmedizin Leipzig, Liebigstr. 22, 04103, Leipzig, Deutschland. gertraud.stocker@medizin.uni-leipzig.de.
R ThiemeKlinik und Poliklinik für Viszeral‑, Transplantations‑, Thorax- und Gefäßchirurgie, Department für Operative Medizin (DOPM), Universitätsklinikum Leipzig, Leipzig, Deutschland.
F LordickKlinik für Onkologie, Gastroenterologie, Hepatologie, Pneumologie und Infektiologie, Universitätsmedizin Leipzig, Liebigstr. 22, 04103, Leipzig, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

According to current German and European clinical practice guidelines perioperative chemotherapy is the recommended standard of care for localized gastric cancer beyond early cancers, i.e. in stage IB (T2 N0 M0 and T1 N1 M0) or greater. For patients who are able to tolerate intensive chemotherapy, the FLOT regimen (5-fluorouracil, folinic acid, oxaliplatin, docetaxel) should be administered preoperatively and postoperatively for four cycles each. Locally advanced nonmetastatic adenocarcinoma of the esophagogastric junction (AEG) should be treated with perioperative chemotherapy as for gastric cancer or alternatively with neoadjuvant chemoradiotherapy. The best approach for AEG is currently being investigated in ongoing clinical trials. The recommendation of perioperative treatment applies to all histopathological subtypes of gastric cancer. The article summarizes the contemporary data and provides an outlook on current progress in the field of medicinal perioperative treatment.

Indexed as

Esophageal NeoplasmsStomach NeoplasmsAntineoplastic Combined Chemotherapy ProtocolsBiomarkersEsophagogastric JunctionFluorouracilHumansNeoadjuvant TherapyBiomarkersFluorouracilAdenocarcinoma of the esophagogastric junctionChemotherapyFLOT regimenNeoadjuvant chemoradiotherapyTreatment guidelines

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.