Evidence map›Paper›PMID 33565879›Full record

ArticleJournal of natural products2021

Leveraging Peptaibol Biosynthetic Promiscuity for Next-Generation Antiplasmodial Therapeutics.

Jin Woo Lee, Jennifer E Collins, Karen L Wendt, Debopam Chakrabarti, Robert H Cichewicz

Open access · greenAbstract read
In one paragraph

Article in Journal of natural products, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 29 citations in OpenAlex.

  1. Draft genome sequence of the peptaibol producerMicrobiology resource announcements · 2026
    Article
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  5. Genome-Guided Metabolomic Profiling of Peptaibol-ProducingInternational journal of molecular sciences · 2025
    Article
  6. Fungal-derived methyldeoxaphomins targetProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jin Woo LeeNatural Products Discovery Group, Institute for Natural Products Applications and Research Technologies, Department of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, Norman, Oklahoma 73019, United States.
Jennifer E CollinsDivision of Molecular Microbiology, Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida 32826, United States.ORCID 0000-0002-1195-4630
Karen L WendtNatural Products Discovery Group, Institute for Natural Products Applications and Research Technologies, Department of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, Norman, Oklahoma 73019, United States.
Debopam ChakrabartiDivision of Molecular Microbiology, Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida 32826, United States.
Robert H CichewiczNatural Products Discovery Group, Institute for Natural Products Applications and Research Technologies, Department of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, Norman, Oklahoma 73019, United States.ORCID 0000-0003-0744-4117
University of Oklahoma · USUniversity of Central Florida · US

Funding

Novel Antimalarials from FungiR01AI154777 · NIAID · UNIVERSITY OF CENTRAL FLORIDA · PI CHAKRABARTI, DEBOPAM, CICHEWICZ, ROBERT HENRY · 2020 to 2024
$3.8M
Discovery of Novel Antimalarial Compounds from FungiR21AI143052 · NIAID · UNIVERSITY OF CENTRAL FLORIDA · PI CHAKRABARTI, DEBOPAM, CICHEWICZ, ROBERT HENRY · 2019 to 2020
$423k
NIAID NIH HHS R01 AI154777NIAID NIH HHS R21 AI143052
6 · The paper itself

Abstract

Malaria remains a worldwide threat, afflicting over 200 million people each year. The emergence of drug resistance against existing therapeutics threatens to destabilize global efforts aimed at controlling

Indexed as

AntimalarialsBiological ProductsDrug ResistanceHep G2 CellsHumansHypocreaMolecular StructurePennsylvaniaPeptaibolsPlasmodium falciparumSoil MicrobiologyTexasTrichodermaAntimalarialsBiological ProductsPeptaibols

Identifiers

PMID33565879
PMCPMC7941592
OpenAlexW3127175464

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.