Evidence map›Paper›PMID 33565263›Full record

ArticleInternational wound journal2021

Detection of bacterial fluorescence from in vivo wound biofilms using a point-of-care fluorescence imaging device.

Andrea J Lopez, Laura M Jones, Landrye Reynolds, Rachel C Diaz, Isaiah K George, William Little, Derek Fleming, Anna D'souza, Monique Y Rennie, Kendra P Rumbaugh and 1 more

Open access · goldAbstract read
In one paragraph

Article in International wound journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. A Scoping Review of Fluorescence Imaging: A Promising New Technology for Bacterial Detection in Burn Wounds.Journal of burn care & research : official publication of the American Burn Association · 2026
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  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Determination of the Course of Cyan Fluorescence ofDiagnostics (Basel, Switzerland) · 2024
    Article
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  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Andrea J LopezDepartment of Honors Studies, Texas Tech University, Lubbock, Texas, USA.
Laura M JonesMolecuLight Inc, Toronto, Ontario, Canada.
Landrye ReynoldsDepartment of Honors Studies, Texas Tech University, Lubbock, Texas, USA.
Rachel C DiazDepartment of Honors Studies, Texas Tech University, Lubbock, Texas, USA.
Isaiah K GeorgeDepartment of Honors Studies, Texas Tech University, Lubbock, Texas, USA.
William LittleDepartment of Honors Studies, Texas Tech University, Lubbock, Texas, USA.
Derek FlemingDepartment of Surgery, Texas Tech University Health Sciences Center, Lubbock, Texas, USA.
Anna D'souzaMolecuLight Inc, Toronto, Ontario, Canada.
Monique Y RennieMolecuLight Inc, Toronto, Ontario, Canada.
Kendra P RumbaughDepartment of Surgery, Texas Tech University Health Sciences Center, Lubbock, Texas, USA.
Allie Clinton SmithDepartment of Honors Studies, Texas Tech University, Lubbock, Texas, USA.
Texas Tech University · USOntario Council of University Libraries · CATexas Tech University Health Sciences Center · US

Funding

MolecuLight Inc.
6 · The paper itself

Abstract

Wound biofilms must be identified to target disruption and bacterial eradication but are challenging to detect with standard clinical assessment. This study tested whether bacterial fluorescence imaging could detect porphyrin-producing bacteria within a biofilm using well-established in vivo models. Mouse wounds were inoculated on Day 0 with planktonic bacteria (n = 39, porphyrin-producing and non-porphyrin-producing species, 10

Indexed as

Wound InfectionAnimalsBacteriaBiofilmsMiceOptical ImagingPoint-of-Care Systemsbiofilmsfluorescenceoptical imagingporphyrinswounds

Identifiers

PMID33565263
PMCPMC8450799
OpenAlexW3128196566

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.