Evidence map›Paper›PMID 33565234›Full record

ArticleJournal of sleep research2021

Working memory deficits in patients with idiopathic restless legs syndrome are associated with abnormal theta-band neural synchrony.

Kwang Su Cha, Jun-Sang Sunwoo, Jung-Ick Byun, Tae-Joon Kim, Jung-Won Shin, Kyung Hwan Kim, Ki-Young Jung

Open access · hybridAbstract read
In one paragraph

Article in Journal of sleep research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Kwang Su ChaDepartment of Neurology, Seoul National University Hospital, Seoul, South Korea.ORCID 0000-0002-7710-8648
Jun-Sang SunwooDepartment of Neurosurgery, Seoul National University Hospital, Seoul, South Korea.ORCID 0000-0001-8834-0568
Jung-Ick ByunDepartment of Neurology, Kyung Hee University Hospital at Gangdong, Seoul, South Korea.
Tae-Joon KimDepartment of Neurology, Ajou University School of Medicine, Suwon, South Korea.
Jung-Won ShinDepartment of Neurology, CHA Bundang Medical Center, CHA University, Seongnam, South Korea.
Kyung Hwan KimDepartment of Biomedical Engineering, College of Health Science, Yonsei University, Wonju, South Korea.
Ki-Young JungDepartment of Neurology, Seoul National University Hospital, Seoul, South Korea.
Seoul National University Hospital · KRAjou University · KRCHA University Bundang Medical Center · KRKyung Hee University Hospital at Gangdong · KRSeoul National University · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cognitive impairment, particularly prefrontal function, has been reported in patients with restless legs syndrome. However, working memory performance in patients with restless legs syndrome remains uncertain. The present study aimed to examine working memory performance in patients with restless legs syndrome by investigating electroencephalography theta-band oscillations within task-relevant brain regions and the synchronization among oscillations during a working memory task. Twelve female idiopathic patients with restless legs syndrome and 12 female healthy controls participated in this study. Nineteen-channel electroencephalography data were recorded while participants performed a Sternberg working memory task. We analysed event-related theta-band activity and interregional theta-band phase synchrony during the memory retrieval phase. The spatial pattern of theta-band phase synchrony was quantified using graph theory measures, including the clustering coefficient, characteristic path length, and small-world propensity. Considerable increases in theta-band activity and theta-band phase synchrony were observed at 600-700 ms in controls and at 650-750 ms in restless legs syndrome subjects after the probe item was presented. During this period, induced theta-band activity showed lower with borderline significance in the restless legs syndrome subjects than in the controls regardless of channel location (F

Indexed as

Memory, Short-TermRestless Legs SyndromeBrainElectroencephalographyFemaleHumansMemory DisordersTheta Rhythmcognitive deficitsevent-related potentialsrestless legs syndrometheta-band activitytheta-band phase synchronyworking memory

Identifiers

PMID33565234
PMCPMC8518982
OpenAlexW3128387702

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.