Evidence map›Paper›PMID 33565219›Full record

ArticleNMR in biomedicine2020

Magnetic resonance spectroscopy in the rodent brain: Experts' consensus recommendations.

Bernard Lanz, Alireza Abaei, Olivier Braissant, In-Young Choi, Cristina Cudalbu, Pierre-Gilles Henry, Rolf Gruetter, Firat Kara, Kejal Kantarci, Phil Lee and 8 more

Open access · greenAbstract read
In one paragraph

Article in NMR in biomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
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  10. Sub-MicroliterJournal of neurochemistry · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 11 institutions in 6 countries.

Bernard LanzLaboratory for Functional and Metabolic Imaging (LIFMET), Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.ORCID https://orcid.org/0000-0001-5136-075X
Alireza AbaeiCore Facility Small Animal Imaging, Ulm University, Ulm, Germany.ORCID https://orcid.org/0000-0003-2287-6495
Olivier BraissantService of Clinical Chemistry, University of Lausanne and University Hospital of Lausanne, Lausanne, Switzerland.ORCID https://orcid.org/0000-0002-8068-3344
In-Young ChoiDepartment of Neurology, University of Kansas Medical Center, Kansas City, Kansas, US.ORCID https://orcid.org/0000-0002-1489-4119
Cristina CudalbuCentre d'Imagerie Biomedicale (CIBM), Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.ORCID https://orcid.org/0000-0003-4582-2465
Pierre-Gilles HenryCenter for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, Minnesota, US.
Rolf GruetterLaboratory for Functional and Metabolic Imaging (LIFMET), Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Firat KaraDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, US.
Kejal KantarciDepartment of Radiology, Mayo Clinic, Rochester, Minnesota, US.
Phil LeeDepartment of Radiology, University of Kansas Medical Center, Kansas City, Kansas, US.ORCID https://orcid.org/0000-0002-2087-8887
Norbert W LutzCNRS, CRMBM, Aix-Marseille University, Marseille, France.ORCID https://orcid.org/0000-0002-8500-2966
Małgorzata MarjańskaCenter for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, Minnesota, US.ORCID https://orcid.org/0000-0002-4727-2447
Vladimír MlynárikHigh Field MR Centre, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Volker RascheCore Facility Small Animal Imaging, Ulm University, Ulm, Germany.
Lijing XinCentre d'Imagerie Biomedicale (CIBM), Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Julien ValetteCommissariat à l'Energie Atomique et aux Energies Alternatives, MIRCen, Fontenay-aux-Roses, France.
Experts' Working Group on Magnetic resonance spectroscopy in the rodent brain
Experts' Working Group on Magnetic resonance spectroscopy in the rodent brain
Centre d'Imagerie BioMedicale · CHMayo Clinic · USUniversität Ulm · DEUniversity of Kansas Medical Center · USUniversity of Minnesota · USCentre National de la Recherche Scientifique · FRÉcole Polytechnique Fédérale de Lausanne · CHMedical University of Vienna · ATUniversité Paris-Sud · FRUniversity Hospital of Lausanne · CHUniversity of Nottingham · GB

Funding

Technology and Remote Assessment CoreU19AG063911 · NIA · MAYO CLINIC ROCHESTER · PI Bradley F Boeve · 2019 to 2026
$120.9M
TDP-43 Loss-of-Function: Biology to BiomarkersP01AG019724 · NIA · UNIVERSITY OF PENNSYLVANIA · PI Jennifer Merrilees · 2002 to 2026
$67.2M
Research Education ComponentP30AG062677 · NIA · MAYO CLINIC ROCHESTER · PI NILUFER ERTEKIN-TANER · 2019 to 2026
$33.5M
Longitudinal Imaging Biomarkers of Prodromal DLBU01NS100620 · NINDS · MAYO CLINIC ROCHESTER · PI Bradley F Boeve, KEJAL KANTARCI · 2017 to 2026
$19.2M
TRD4 - Ultrahigh Field Engineering and SafetyP41EB027061 · NIBIB · UNIVERSITY OF MINNESOTA · PI Gregory John Metzger, KAMIL UGURBIL · 2019 to 2026
$11.7M
Institutional Center Cores for Advanced NeuroimagingP30NS076408 · NINDS · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2012 to 2020
$4.2M
Partnership for Magnetic Resonance Spectroscopy Biomarker Development-SupplementR01NS080816 · NINDS · UNIVERSITY OF MINNESOTA · PI OZ, GULIN · 2015 to 2019
$3.2M
NIA NIH HHS P01 AG019724NIA NIH HHS P30 AG062677NIA NIH HHS U19 AG063911NIBIB NIH HHS P41 EB027061NINDS NIH HHS P30 NS076408NINDS NIH HHS R01 NS080816NINDS NIH HHS U01 NS100620
6 · The paper itself

Abstract

In vivo MRS is a non-invasive measurement technique used not only in humans, but also in animal models using high-field magnets. MRS enables the measurement of metabolite concentrations as well as metabolic rates and their modifications in healthy animals and disease models. Such data open the way to a deeper understanding of the underlying biochemistry, related disturbances and mechanisms taking place during or prior to symptoms and tissue changes. In this work, we focus on the main preclinical

Indexed as

anesthesiabrain metabolismconsensus reviewdynamic MRSneurochemical profilepreclinical MRS

Identifiers

PMID33565219
PMCPMC9429976
OpenAlexW3081857945

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.