Evidence map›Paper›PMID 33565114›Full record

ArticleAnnals of the New York Academy of Sciences2021

Morality is in the eye of the beholder: the neurocognitive basis of the "anomalous-is-bad" stereotype.

Clifford I Workman, Stacey Humphries, Franziska Hartung, Geoffrey K Aguirre, Joseph W Kable, Anjan Chatterjee

Open access · hybridAbstract read
In one paragraph

Article in Annals of the New York Academy of Sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Face Value: Beauty, Punishment, and the Moral Politics of Appearance.Behavioral sciences (Basel, Switzerland) · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Clifford I WorkmanDepartment of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0002-2206-0325
Stacey HumphriesDepartment of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0001-9681-660X
Franziska HartungDepartment of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0001-5660-2324
Geoffrey K AguirreDepartment of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0002-4028-3100
Joseph W KablePenn Brain Science Center, University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0001-6495-9040
Anjan ChatterjeeDepartment of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0002-9092-8560
Penn Center for AIDS Research · USUniversity of Pennsylvania · US

Funding

The good, the bad, and the different: Understanding stigma towards people with facial differencesF32DE029407 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI WORKMAN, CLIFFORD I. · 2019 to 2021
$208k
NIDCR NIH HHS F32 DE029407NIDCR NIH HHS F32DE029407
6 · The paper itself

Abstract

Are people with flawed faces regarded as having flawed moral characters? An "anomalous-is-bad" stereotype is hypothesized to facilitate negative biases against people with facial anomalies (e.g., scars), but whether and how these biases affect behavior and brain functioning remain open questions. We examined responses to anomalous faces in the brain (using a visual oddball paradigm), behavior (in economic games), and attitudes. At the level of the brain, the amygdala demonstrated a specific neural response to anomalous faces-sensitive to disgust and a lack of beauty but independent of responses to salience or arousal. At the level of behavior, people with anomalous faces were subjected to less prosociality from participants highest in socioeconomic status. At the level of attitudes, we replicated previously reported negative character evaluations made about individuals with facial anomalies, and further identified explicit biases directed against them as a group. Across these levels of organization, the specific amygdala response to facial anomalies correlated with stronger just-world beliefs (i.e., people get what they deserve), less dispositional empathic concern, and less prosociality toward people with facial anomalies. Characterizing the "anomalous-is-bad" stereotype at multiple levels of organization can reveal underappreciated psychological burdens shouldered by people who look different.

Indexed as

CognitionMoralsStereotypingAdultAmygdalaEmotionsFacial ExpressionFemaleHumansMagnetic Resonance ImagingMaleMiddle Agedamygdaladisgustempathyfacesmoralityneuroaesthetics

Identifiers

PMID33565114
PMCPMC8247878
OpenAlexW3127453023

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.