ArticleBiological trace element research2021
Protective Effect of Vitamin E on Cadmium-Induced Renal Oxidative Damage and Apoptosis in Rats.
Article in Biological trace element research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Renal protective effects of vitamin E for drug-induced kidney injury: a meta-analysis.Frontiers in pharmacology · 2025Pooled it
- PERK Signaling Pathway Mediates the Hepatoprotective Effects of Naringenin Against Cadmium-Induced Liver Injury in Rats.Journal of biochemical and molecular toxicology · 2026Article
- Investigation of the preventive action of rebamipide versus cadmium nephrotoxicity effect in rats.Irish journal of medical science · 2026Article
- Mechanistic insights into the protective effects of vitamin E against olanzapine-induced testicular toxicity: The role of microRNAs in oxidative stress and apoptosis.Iranian journal of basic medical sciences · 2026Article
- Protective effect of the bee bread on cadmium-induced testicular toxicity in rats.Veterinary research forum : an international quarterly journal · 2026Article
- Molecular Changes Associated with Inflammation and Reproduction in Cadmium-Induced Testicular Toxicity: Mitigating Effect of Lactobacillus plantarum.Biological trace element research · 2025Article
- Metal mechanisms of mitochondrial toxicity: recent review of arsenic, cadmium, and lead-induced nephrotoxicity.Environmental science and pollution research international · 2025Review
- Vitamin E Inhibits Oxidative Stress and Inflammation in Stress-Induced Gastritis via Modulating Nrf2 and NF-κB Signalling Pathways.Journal of cellular and molecular medicine · 2025Article
- Anti-nephrotoxic, antioxidant and anti-inflammatory efficiency ofOpen veterinary journal · 2025Article
- Effects of edible bird's nest and EDTA on cadmium toxicity exposed rats' embryo production, quality, and pre- and post-embryo transfer pregnancy rates.Journal of advanced veterinary and animal research · 2024Article
- Evaluation of the Potential Cytoprotective Effect of Melatonin in Comparison with Vitamin E and Trolox against CdInternational journal of molecular sciences · 2024Article
- The Effects of Seleno-Methionine in Cadmium-Challenged Human Primary Chondrocytes.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Nickel Induces Pyroptosis via the Nrf2/NLRP3 Pathway in Kidney of Mice.Biological trace element research · 2024Article
- Overexpression of Lias Gene Alleviates Cadmium-Induced Kidney Injury in Mice Involving Multiple Effects: Metabolism, Oxidative Stress, and Inflammation.Biological trace element research · 2024Article
- Heavy Metal Exposure: Molecular Pathways, Clinical Implications, and Protective Strategies.Antioxidants (Basel, Switzerland) · 2024Review
- Role of vitamin E on bovine skeletal-muscle-derived cells from Korean native cattle under heat treatment.Journal of animal science · 2024Article
- The antioxidant and anti-apoptotic properties of vitamins A, C and E in heart tissue of rats exposed to zinc oxide nanoparticles.Molecular biology reports · 2023Article
- The Cd/Zn Axis: Emerging Concepts in Cellular Fate and Cytotoxicity.Biomolecules · 2023Article
- Antioxidant Effects of Bioactive Glasses (BGs) and Their Significance in Tissue Engineering Strategies.Molecules (Basel, Switzerland) · 2022Review
- Curative Potential of Substances with Bioactive Properties to Alleviate Cd Toxicity: A Review.International journal of environmental research and public health · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 3 institutions in 1 country.
Funding
Abstract
Cadmium (Cd), a widely distributed heavy metal, is extremely toxic to the kidney. Vitamin E (VE) is an important antioxidant in the body. It is known that VE exerts a protective effect on renal oxidative damage caused by Cd, but the effect and mechanism of VE on apoptosis are not fully understood. Thus, we conducted this study to explore the protective effect of VE on Cd-induced renal apoptosis and to elucidate its potential mechanism. Thirty-two 9-week-old male Sprague-Dawley rats were randomly divided into four groups, namely control, VE (100 mg/kg VE), Cd (5 mg/kg CdCl
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.