Evidence map›Paper›PMID 33564964›Full record

GuidelineSurgical endoscopy2021

SAGES guidelines for the use of peroral endoscopic myotomy (POEM) for the treatment of achalasia.

Geoffrey P Kohn, Rebecca C Dirks, Mohammed T Ansari, Jason Clay, Christy M Dunst, Lars Lundell, Jeffrey M Marks, Daniela Molena, Ceciel Rooker, Payal Saxena and 4 more

Abstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in Surgical endoscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 4 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 4 syntheses or guidelines pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Pooled it
  5. Achalasia in Geriatric Patients: A Comprehensive Overview.Digestive diseases and sciences · 2026
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Surgical management of achalasia.Abdominal radiology (New York) · 2025
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Achalasia and Hiatal Hernia: A Rare Association and a Therapeutic Challenge.Journal of neurogastroenterology and motility · 2023
    Article
  20. The Results of Pneumatic Balloon Dilatation Treatment in Children with Achalasia: A Single-Center Experience.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 12 institutions in 7 countries.

Geoffrey P KohnDepartment of Surgery, Eastern Health Clinical School, Monash University, Clayton, VIC, Australia. gkohn@uppergi.net.ORCID 0000-0002-7708-7859
Rebecca C DirksDepartment of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
Mohammed T AnsariSchool of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Jason ClayInternational Foundation for Gastrointestinal Disorders, Mount Pleasant, USA.
Christy M DunstThe Oregon Clinic, Portland, OR, USA.
Lars LundellDivision of Surgery, CLINTEC, Karolinska Institutet, Stockholm, Sweden.
Jeffrey M MarksDepartment of Surgery, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Daniela MolenaDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Ceciel RookerInternational Foundation for Gastrointestinal Disorders, Mount Pleasant, USA.
Payal SaxenaAW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Newtown, Sydney, NSW, Australia.
Lee SwanstromInstitut de Chirugie, IHU Strasbourg, Strasbourg, France.
Reuben K WongDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Aurora D PryorDepartment of Surgery, Stony Brook University, Stony Brook, NY, USA.
Dimitrios StefanidisDepartment of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
Indiana University School of MedicineInternational Foundation for Functional Gastrointestinal Disorders · USEastern Health · AUInstitut de Chirurgie Guidée par l'Image · FRMemorial Sloan Kettering Cancer Center · USNational University of Singapore · SGOdense University Hospital · DKOregon Clinic · USStony Brook University · USThe University of Sydney · AUUniversity Hospitals of Cleveland · USUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeroral endoscopic myotomy (POEM) is increasingly used as primary treatment for esophageal achalasia, in place of the options such as Heller myotomy (HM) and pneumatic dilatation (PD)

objectiveThese evidence-based guidelines from the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) intend to support clinicians, patients and others in decisions about the use of POEM for treatment of achalasia.

resultsThe panel agreed on 4 recommendations for adults and children with achalasia.

conclusionsStrong recommendation for the use of POEM over PD was issued unless the concern of continued postoperative PPI use remains a key decision-making concern to the patient. Conditional recommendations included the option of using either POEM or HM with fundoplication to treat achalasia, and favored POEM over HM for achalasia subtype III.

Indexed as

AdultChildEsophageal AchalasiaEsophageal Sphincter, LowerEsophagoscopyFundoplicationHeller MyotomyHumansNatural Orifice Endoscopic SurgeryPostoperative CarePostoperative ComplicationsClinical practice guidelinesEsophageal achalasiaHeller myotomyPneumatic dilatationPOEM procedure

Identifiers

PMID33564964
OpenAlexW3126369925

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.