Evidence map›Paper›PMID 33564945›Full record

ArticleJournal of general internal medicine2021

Advancing Diagnostic Safety Research: Results of a Systematic Research Priority Setting Exercise.

Laura Zwaan, Robert El-Kareh, Ashley N D Meyer, Jacky Hooftman, Hardeep Singh

Abstract read
In one paragraph

Article in Journal of general internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Observational
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Laura ZwaanErasmus Medical Center Rotterdam, Institute of Medical Education Research Rotterdam, Rotterdam, The Netherlands. l.zwaan@erasmusmc.nl.ORCID 0000-0003-3940-1699
Robert El-KarehDepartment of Medicine, University of California at San Diego, San Diego, CA, USA.
Ashley N D MeyerCenter for Innovations in Quality, Effectiveness and Safety, Michael E. DeBakey VA Medical Center, Houston, TX, USA.
Jacky HooftmanErasmus Medical Center Rotterdam, Institute of Medical Education Research Rotterdam, Rotterdam, The Netherlands.
Hardeep SinghCenter for Innovations in Quality, Effectiveness and Safety, Michael E. DeBakey VA Medical Center, Houston, TX, USA.

Funding

Decentralized differentially-private methods for dynamic data release and analysisR01GM118609 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JIANG, XIAOQIAN, OHNO-MACHADO, LUCILA · 2017 to 2020
$2.3M
Application of a Machine Learning to Enhance e-Triggers to Detect and Learn from Diagnostic Safety EventsR01HS027363 · AHRQ · BAYLOR COLLEGE OF MEDICINE · PI SINGH, HARDEEP · 2019 to 2021
$1.5M
Understanding physicians' diagnostic accuracy in the EHR eraIK2HX002586 · VA · MICHAEL E DEBAKEY VA MEDICAL CENTER · PI MEYER, ASHLEY ND · 2019 to 2023
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AHRQ HHS R01 HS027363HSRD VA IK2 HX002586NIGMS NIH HHS R01 GM118609VA CIN13-413
6 · The paper itself

Abstract

backgroundDiagnostic errors are a major source of preventable harm but the science of reducing them remains underdeveloped.

objectiveTo identify and prioritize research questions to advance the field of diagnostic safety in the next 5 years.

participantsNinety-seven researchers and 42 stakeholders were involved in the identification of the research priorities.

designWe used systematic prioritization methods based on the Child Health and Nutrition Research Initiative (CHNRI) methodology. We first invited a large international group of expert researchers in various disciplines to submit research questions while considering five prioritization criteria: (1) usefulness, (2) answerability, (3) effectiveness, (4) potential for translation, and (5) maximal potential for effect on diagnostic safety. After consolidation, these questions were prioritized at an in-person expert meeting in April 2019. Top-ranked questions were subsequently reprioritized through scoring on the five prioritization criteria using an online questionnaire. We also invited non-research stakeholders to assign weights to the five criteria and then used these weights to adjust the final prioritization score for each question. KEY

resultsOf the 207 invited researchers, 97 researchers responded and 78 submitted 333 research questions which were then consolidated. Expert meeting participants (n = 21) discussed questions in different breakout sessions and prioritized 50, which were subsequently reduced to the top 20 using the online questionnaire. The top 20 questions addressed mostly system factors (e.g., implementation and evaluation of information technologies), teamwork factors (e.g., role of nurses and other health professionals in the diagnostic process), and strategies to engage patients in the diagnostic process.

conclusionsTop research priorities for advancing diagnostic safety in the short-term include strengthening systems and teams and engaging patients to support diagnosis. High-priority areas identified using these systematic methods can inform an actionable research agenda for reducing preventable diagnostic harm.

Indexed as

Biomedical ResearchChild HealthChildExerciseHumansResearch DesignResearch PersonnelSurveys and Questionnairesdiagnostic safetymedical errorpatient safetyresearch priorities

Identifiers

PMID33564945
PMCPMC8481519

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.