Evidence map›Paper›PMID 33564714›Full record

ArticleAdvanced biosystems2018

Biomimetic microgels with controllable deformability improve healing outcomes.

Erin P Sproul, Seema Nandi, Colleen Roosa, Luisa Schreck, Ashley C Brown

Open access · greenAbstract read
In one paragraph

Article in Advanced biosystems, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Biomimetic Hydrogels to Promote Wound Healing.Frontiers in bioengineering and biotechnology · 2021
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Nanomedicines: A Potential Treatment for Blood Disorder Diseases.Frontiers in bioengineering and biotechnology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Erin P SproulJoint Department of Biomedical Engineering, North Carolina State University and the University of North Carolina-Chapel Hill, Raleigh, NC USA.
Seema NandiJoint Department of Biomedical Engineering, North Carolina State University and the University of North Carolina-Chapel Hill, Raleigh, NC USA.
Colleen RoosaJoint Department of Biomedical Engineering, North Carolina State University and the University of North Carolina-Chapel Hill, Raleigh, NC USA.
Luisa SchreckSchool of Material Science and Engineering, University of New South Wales, Sydney, Australia.
Ashley C BrownJoint Department of Biomedical Engineering, North Carolina State University and the University of North Carolina-Chapel Hill, Raleigh, NC USA.
North Carolina State University · USUNSW Sydney · AU

Funding

Ultrasound enhanced platelet-like particle therapy for accelerated wound repairR21AR071017 · NIAMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI BROWN, ASHLEY CARSON, MULLER, MARIE · 2017 to 2018
$343k
NIAMS NIH HHS R21 AR071017
6 · The paper itself

Abstract

Platelets mediate hemostasis by aggregating and binding to fibrin to promote clotting. Over time, platelets contract the fibrin network to induce clot retraction, which contributes to wound healing outcomes by increasing clot stability and improving blood flow to ischemic tissue. In this study, we describe the development of hollow platelet-like particles (PLPs) that mimic the native platelet function of clot retraction in a controlled manner and demonstrate that clot retraction-inducing PLPs promote healing

Indexed as

biomimeticfibrinmicrogelSynthetic plateletwound healing

Identifiers

PMID33564714
PMCPMC7869964
OpenAlexW2887928688

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.