Evidence map›Paper›PMID 33564531›Full record

ArticleCureus2021

Alarming Eosinophilia From Dobutamine Infusion.

Naji Maaliki, Aleem A Ali, Christopher Izzo, Hamel Patel, Steve Antoine

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 100% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 0 citations in OpenAlex.

  1. Incriminating the inotrope: Dobutamine, eosinophilia, and myocarditis.The journal of allergy and clinical immunology. Global · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Naji MaalikiInternal Medicine, University of Florida College of Medicine, Jacksonville, USA.
Aleem A AliInternal Medicine, University of Florida College of Medicine, Jacksonville, USA.
Christopher IzzoInternal Medicine, University of Florida College of Medicine, Jacksonville, USA.
Hamel PatelInternal Medicine, University of Florida College of Medicine, Jacksonville, USA.
Steve AntoineCardiology, University of Florida College of Medicine, Jacksonville, USA.
University of Florida · USFlorida College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 49-year-old male with a history of nonischemic heart failure with reduced ejection fraction, hypertension, diabetes was admitted for cardiogenic shock. Treatment started with a high dose of dobutamine infusion. While the patient's volume status improved, his clinical status declined as he became febrile and hypotensive. He was found to have severe dobutamine-induced eosinophilia, corrected only upon dobutamine cessation and steroid administration. A comprehensive investigation ruled out other potential etiologies. Peripheral eosinophilia is a rare adverse effect associated with dobutamine, leading to a significant deterioration in already decompensated patients.

Indexed as

cardiogenic shockcritical care cardiologydobutaminedrug-induced eosinophiliaeosinophilaheart failurehyper-eosinophilia syndrome

Identifiers

PMID33564531
PMCPMC7863021
OpenAlexW3119079789

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.